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血管外科医生行股直肌肌皮瓣移植术治疗股动脉重建术后复杂腹股沟创面的疗效。

Outcome of rectus femoris muscle flaps performed by vascular surgeons for the management of complex groin wounds after femoral artery reconstructions.

机构信息

Department of Endovascular and Vascular Surgery, Geisinger Medical Center, Danville, Pa.

Department of Endovascular and Vascular Surgery, Geisinger Medical Center, Danville, Pa.

出版信息

J Vasc Surg. 2020 Mar;71(3):905-911. doi: 10.1016/j.jvs.2019.05.052. Epub 2019 Aug 27.

Abstract

OBJECTIVE

Groin wound complications after femoral artery reconstructions are highly morbid and notoriously difficult to treat. Successful techniques include long-term antibiotic therapy, operative débridement, and muscle flap coverage. Historically, more complex muscle flap coverage, such as a rectus femoris muscle flap (RFF), has been performed by plastic and reconstructive surgeons. In this study, the experience of vascular surgeons performing RFF in the management of wound complications after femoral artery reconstructions is reported.

METHODS

Clinical data between 2012 and 2018 were retrospectively analyzed. Data were summarized, and standard statistical analysis was performed.

RESULTS

There were 23 patients who underwent 24 RFFs for coverage of complex groin wounds after femoral artery reconstructions. One of the 23 patients underwent bilateral RFFs. In this study cohort, patients had a median age of 67.5 years, and 79% (n = 19) were male. Median body mass index was 28.0 kg/m, and 38% of patients were classified as obese on the basis of body mass index criteria. A history of tobacco use was present in 88%; however, only 29% were current smokers. Diabetes was present in 38% of patients and chronic kidney disease in 29%. Of the 24 RFFs, 14 (58%) were constructed in patients with reoperative groin surgery resulting in the need for muscle flap coverage. Femoral endarterectomy was the most common index procedure (46%), followed by infrainguinal leg bypass surgery (17%) and aortobifemoral bypass (17%). Grafts used during the original reconstruction included 12 bovine pericardial patches (50%), 6 Dacron grafts (25%), 4 PTFE grafts (17%), and 2 autogenous reconstructions (8%). Microbiology data identified 33% of patients (n = 8) to have gram-positive bacterial infections alone, 21% (n = 5) to have gram-negative infections alone, and 29% (n = 7) to have polymicrobial infections; 4 patients (13%) had negative intraoperative culture data. Median hospital stay after RFF was 8 days, and median follow-up time was 29.3 months. Major amputation was avoided in 20 of 24 limbs (83%) undergoing RFF. Eight patients underwent intentional graft or patch explantation (33%) before RFF, whereas 14 of the remaining 15 patients (93%) had successful salvage of the graft or patch after RFF. Two of the patients (13%) who underwent RFF with the intention of salvaging a prosthetic graft or patch required later graft excision. After RFF, 30-day and 1-year survival was 96% and 87%, respectively.

CONCLUSIONS

RFF coverage of complex groin wounds after femoral artery reconstructions may safely be performed by vascular surgeons with excellent outcomes.

摘要

目的

股动脉重建后腹股沟伤口并发症的发病率较高,且治疗难度极大。成功的治疗方法包括长期使用抗生素、手术清创以及肌瓣覆盖。过去,更复杂的肌瓣覆盖,如股直肌肌瓣(RFF),通常由整形和重建外科医生进行。本研究报告了血管外科医生在股动脉重建后治疗腹股沟伤口并发症时使用 RFF 的经验。

方法

回顾性分析 2012 年至 2018 年的临床数据。对数据进行总结,并进行标准统计分析。

结果

共有 23 例患者接受了 24 例 RFF,以覆盖股动脉重建后复杂的腹股沟伤口。23 例患者中有 1 例接受了双侧 RFF。在本研究队列中,患者的中位年龄为 67.5 岁,79%(n=19)为男性。中位体重指数为 28.0kg/m,根据体重指数标准,38%的患者为肥胖。88%的患者有吸烟史,但只有 29%的患者目前吸烟。38%的患者患有糖尿病,29%的患者患有慢性肾脏病。24 例 RFF 中,14 例(58%)患者因再次腹股沟手术而需要肌瓣覆盖。股内膜切除术是最常见的指数手术(46%),其次是下肢旁路手术(17%)和腹主动脉-股动脉旁路手术(17%)。最初重建中使用的移植物包括 12 个牛心包补片(50%)、6 个 Dacron 移植物(25%)、4 个 PTFE 移植物(17%)和 2 个自体重建(8%)。微生物学数据显示,33%(n=8)的患者为单纯革兰氏阳性细菌感染,21%(n=5)为单纯革兰氏阴性感染,29%(n=7)为混合感染;4 名患者(13%)的术中培养数据为阴性。RFF 后的中位住院时间为 8 天,中位随访时间为 29.3 个月。24 条肢体中有 20 条(83%)进行 RFF 后避免了大截肢。在进行 RFF 之前,有 8 名患者进行了有意的移植物或补片切除(33%),而在其余 15 名患者中的 14 名(93%)中,在 RFF 后成功挽救了移植物或补片。2 名接受 RFF 以挽救人工移植物或补片的患者后来需要切除移植物。RFF 后 30 天和 1 年的生存率分别为 96%和 87%。

结论

血管外科医生可以安全地进行股动脉重建后复杂腹股沟伤口的 RFF 覆盖,且治疗效果良好。

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