Ortiz-Fullana José L, Sánchez Cristina, Pagán Pedro, Mulero-Soto Patricia, Dieppa-Barnes Gabriel, Santini-Domínguez Rafael, Martinez-Trabal Jorge L
Department of Vascular Surgery, San Luke's Memorial Hospital, Ponce, Puerto Rico.
School of Medicine, Ponce Health Sciences University, Ponce, Puerto Rico.
J Vasc Surg Cases Innov Tech. 2023 Nov 4;10(1):101365. doi: 10.1016/j.jvscit.2023.101365. eCollection 2024 Feb.
We aim to describe and report on a novel graft preservation technique using a human gelatin thrombin matrix with rifampin for the treatment of vascular graft infections. Eight patients with vascular graft infections were included, one with bilateral infections, for a total of nine cases from January 2016 through June 2021. All the patients underwent wound exploration and placement of human gelatin thrombin matrix with rifampin. No deaths or allergic reactions had been reported at the 30-day follow-up, with only one major amputation. The graft and limb salvage rates were 77.8% at the 1-year follow-up. The mean time to a major amputation was 122 days, and the mean time to graft excision was 30 days.
我们旨在描述并报告一种使用含利福平的人明胶凝血酶基质治疗血管移植物感染的新型移植物保存技术。纳入了8例血管移植物感染患者，其中1例为双侧感染，从2016年1月至2021年6月共9例。所有患者均接受了伤口探查并放置了含利福平的人明胶凝血酶基质。30天随访时未报告死亡或过敏反应，仅1例进行了大截肢。1年随访时移植物和肢体挽救率为77.8%。大截肢的平均时间为122天，移植物切除的平均时间为30天。
