Department of Biochemistry, Vanderbilt University School of Medicine Basic Sciences, Nashville, TN, 37240-7917, USA.
J Membr Biol. 2019 Dec;252(6):541-548. doi: 10.1007/s00232-019-00090-5. Epub 2019 Aug 30.
A subjective account is presented of challenges and excitement of being a postdoctoral trainee in the lab of James H. Prestegard at Yale University in New Haven, Connecticut from 1989 to 1991. This includes accounts of the early development of bicelles and of oriented sample NMR results that contributed to our modern understanding of the properties of the water-lipid interface of disordered phase biological membranes.
本文以主观的视角讲述了作者在 1989 年至 1991 年期间在康涅狄格州纽黑文市耶鲁大学 James H. Prestegard 实验室作为博士后研究员所面临的挑战和感到的兴奋。这包括双脂体早期发展的描述,以及各向异性样品 NMR 结果的描述,这些结果有助于我们现代理解无序相生物膜的水-脂界面的特性。