一只患有子宫蓄脓的母犬的子宫内膜黏液腺癌——病例报告

Endometrial Mucinous Adenocarcinoma in a Bitch With Pyometra-A Case Report.

作者信息

Špoljarić Branimira, Vince Silvijo, Folnožić Ivan, Medven Zagradišnik Lidija, Huber Doroteja, Gudan Kurilj Andrea, Grabarević Željko

机构信息

University of Zagreb, Faculty of Veterinary Medicine, Clinic for Obstetrics and Reproduction, Zagreb, Croatia.

出版信息

Top Companion Anim Med. 2019 Sep;36:16-21. doi: 10.1053/j.tcam.2019.06.002. Epub 2019 Jun 25.

DOI:10.1053/j.tcam.2019.06.002

PMID:31472724

Abstract

Endometrial adenocarcinomas present rare neoplasia of bitches. This case report describes mucinous endometrial adenocarcinoma in a bitch with concurrent pyometra for the first time. A mass on the uterine stump was removed during surgery of a 13-year-old bitch with clinically suspected pyometra. Histopathology revealed mucinous endometrial adenocarcinoma. The tumor was classified according to human classification, responding to women's type I (endometrioid carcinoma). Immunohistochemistry showed a positive expression of estrogen receptor α, progesterone receptor, p53, and p16 gene, while vimentin was not expressed.

摘要

子宫内膜腺癌在母犬中是一种罕见的肿瘤。本病例报告首次描述了一只患有子宫蓄脓并发黏液性子宫内膜腺癌的母犬。在对一只临床怀疑患有子宫蓄脓的13岁母犬进行手术时，切除了子宫残端上的一个肿块。组织病理学检查显示为黏液性子宫内膜腺癌。该肿瘤根据人类的分类标准进行分类，属于女性I型（子宫内膜样癌）。免疫组织化学显示雌激素受体α、孕激素受体、p53和p16基因呈阳性表达，而波形蛋白未表达。