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糖尿病患者的高血压治疗:重点关注心力衰竭预防。

Hypertension Treatment in Diabetes: Focus on Heart Failure Prevention.

机构信息

Division of Cardiology, Department of Medicine, University of North Carolina, Burnett-Womack Building, 160 Dental Circle, CB# 7075, Chapel Hill, NC 27599, USA.

Division of Cardiology, Department of Medicine, University of North Carolina, Burnett-Womack Building, 160 Dental Circle, CB# 7075, Chapel Hill, NC 27599, USA.

出版信息

Heart Fail Clin. 2019 Oct;15(4):551-563. doi: 10.1016/j.hfc.2019.06.008.

Abstract

Diabetes is strongly associated with development of cardiovascular disease and poor cardiovascular outcomes. Management of hypertension reduces cardiovascular outcomes among patients with diabetes. Many studies have examined the benefits of various classes of antihypertensives among patients with diabetes. Based on these, the American Diabetes Association has advised that all patients (particularly those with microalbuminuria) be treated first with an angiotensin-converting enzyme inhibitor or an aldosterone receptor blocker followed by a calcium channel blocker or diuretic. Recently, sodium glucose transporter 2 inhibitors have been identified for their benefit in blood pressure control and cardiovascular risk reduction in patients with diabetes.

摘要

糖尿病与心血管疾病的发生和不良心血管结局密切相关。高血压的管理可以降低糖尿病患者的心血管结局。许多研究已经研究了各种类别的降压药物在糖尿病患者中的益处。基于这些研究,美国糖尿病协会建议所有患者(特别是那些有微量白蛋白尿的患者)首先使用血管紧张素转换酶抑制剂或醛固酮受体阻滞剂治疗,然后再使用钙通道阻滞剂或利尿剂。最近,钠-葡萄糖共转运体 2 抑制剂因其在控制血压和降低糖尿病患者心血管风险方面的益处而被发现。

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