中医辨证在高血压和糖尿病患者体质辨识中的应用

Application of traditional Chinese medicine syndrome differentiation in identification of body constitution of hypertensive and diabetic patients.

作者信息

Fang Yuxi, Luo Le, Li Ruhui

机构信息

Basic Medical College, Zhejiang Chinese Medical University Hangzhou City, Zhejiang Province, China.

Beijing University of Chinese Medicine Beijing, China.

出版信息

Am J Transl Res. 2021 Oct 15;13(10):12034-12042. eCollection 2021.

PMID:34786139

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8581866/

Abstract

OBJECTIVE

To investigate the application of traditional Chinese medicine (TCM) syndrome differentiation in identification of body constitution of hypertensive and diabetic patients.

METHODS

A total of 110 hypertensive patients with diabetes treated in our hospital were enrolled in this study, and were divided into a study group (SG, n=60) and a control group (CG, n=50) according to different intervention methods. Patients in the CG received conventional western medical intervention for hypertension and diabetes, while patients in the SG received body constitution-identified TCM syndrome differentiation intervention additionally. The changes of blood pressure and plasma glucose during the intervention were compared between the two groups, the clinical effect and quality of life of the two groups were evaluated, and multivariate stepwise Logistic regression analysis on influencing factor of TCM body constitution was conducted.

RESULTS

Compared with that before intervention, the proportion of gentleness constitution in the SG showed a significant increase (<0.05) after intervention. Dynamic analysis during the intervention showed that patients in the SG had lower systolic blood pressure (SBP), diastolic blood pressure (DBP), lower level of fasting plasma glucose (GLU) and 2-h postprandial plasma glucose (2hPG) than the CG from 1 to 12 months after intervention (<0.05). Patients in the SG scored higher than the CG on all SF-36 dimensions after intervention (<0.05). Multivariate stepwise Logistic regression analysis showed that dampness-heat constitution, blood-stasis constitution, Yin-deficiency constitution and phlegm-dampness constitution were the main risk factors for hypertension with diabetes (<0.05).

CONCLUSION

Body constitution-identified TCM syndrome differentiation treatment for hypertensive patients with diabetes is effective, which can significantly improve the plasma glucose and blood pressure indices of patients. Dampness-heat constitution, blood-stasis constitution, Yin-deficiency constitution and phlegm-dampness constitution are the risk factors for hypertension with diabetes.

摘要

目的

探讨中医辨证在高血压合并糖尿病患者体质辨识中的应用。

方法

选取我院收治的110例高血压合并糖尿病患者，根据不同干预方法分为研究组（SG，n = 60）和对照组（CG，n = 50）。CG组患者接受高血压和糖尿病的常规西医干预，而SG组患者额外接受体质辨识的中医辨证干预。比较两组干预期间血压和血糖的变化，评估两组的临床疗效和生活质量，并对中医体质的影响因素进行多因素逐步Logistic回归分析。

结果

与干预前相比，SG组干预后平和质比例显著增加（<0.05）。干预期间的动态分析表明，干预后1至12个月，SG组患者的收缩压（SBP）、舒张压（DBP）、空腹血糖（GLU）水平和餐后2小时血糖（2hPG）均低于CG组（<0.05）。干预后，SG组患者在所有SF - 36维度上的得分均高于CG组（<0.05）。多因素逐步Logistic回归分析表明，湿热质、血瘀质、阴虚质和痰湿质是高血压合并糖尿病的主要危险因素（<0.05）。