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放射性栓塞在胆道和原发性肝癌中的作用。

Role of Radioembolization for Biliary Tract and Primary Liver Cancer.

作者信息

Taylor Amy C, Maddirela Dilip, White Sarah B

机构信息

Radiology Consultants of Little Rock, 9601 Baptist Health Drive, Suite 1100, Little Rock, AR 72205, USA.

Department of Radiology, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.

出版信息

Surg Oncol Clin N Am. 2019 Oct;28(4):731-743. doi: 10.1016/j.soc.2019.07.001.

Abstract

Hepatocellular carcinoma and intrahepatic cholangiocarcinoma are often amenable to locoregional therapy, including percutaneous ablation, transarterial chemoembolization (TACE), or transarterial radioembolization (TARE). TARE is a technique that delivers a high dose of radiation to the tumor, while limiting the dose to the normal liver parenchyma and the adjacent organs. It has been shown to effectively provide disease control with relatively few toxicities, and in certain cases results in a complete response. It is the preferred therapy as a bridge to liver transplant and can provide necessary compensatory future liver remnant hypertrophy before planned surgical resection.

摘要

肝细胞癌和肝内胆管癌通常适合局部区域治疗,包括经皮消融、经动脉化疗栓塞(TACE)或经动脉放射性栓塞(TARE)。TARE是一种向肿瘤输送高剂量辐射的技术,同时将对正常肝实质和邻近器官的剂量限制在最低水平。已证明它能有效控制疾病,且毒性相对较少,在某些情况下还能实现完全缓解。它是肝移植过渡治疗的首选方法,并且在计划进行手术切除前,可为未来肝脏残余部分提供必要的代偿性肥大。

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