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紧张型头痛患者的自杀倾向及其危险因素:一项多中心病例对照研究。

Suicidality and its risk factors in tension-type headache patients: A multicenter case-control study.

机构信息

Department of Neurology, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.

Department of Neurology, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Republic of Korea.

出版信息

J Clin Neurosci. 2019 Nov;69:21-25. doi: 10.1016/j.jocn.2019.08.084. Epub 2019 Aug 29.

DOI:10.1016/j.jocn.2019.08.084
PMID:31473092
Abstract

This study evaluated suicidality and its risk factors in patients with tension-type headache (TTH). We recruited new patients with TTH who visited general hospitals. We recorded their clinical characteristics and conducted the Headache Impact Test-6 (HIT-6) and the Insomnia Severity Index (ISI) for assessment. We also interviewed the patients to identify major depressive disorder (MDD), generalized anxiety disorder (GAD), and suicidality with the Mini International Neuropsychiatric Interview-Plus Version 5.0.0 (MINI). The frequency of suicidality was compared between TTH patients and healthy controls. Major risk factors for suicidality were also determined. A total of 332 TTH patients with the same number of healthy controls were recruited from five general hospitals. Suicidality was observed in 82 (24.7%) TTH patients. The frequency of suicidality was significantly higher in patients with TTH than in the controls. Furthermore, the frequency of suicidality was higher in patients with chronic TTH (CTTH) than in the controls. The major risk factors for suicidality were MDD, GAD, a low education level, insomnia, chronicity of TTH, and pericranial tenderness. Suicidal ideation or attempt seems to be a common feature in TTH. Therefore, it is important to identify risk factors related to suicidality in TTH patients, which may help reduce suicidality.

摘要

这项研究评估了紧张型头痛(TTH)患者的自杀意念及其危险因素。我们招募了新的 TTH 患者,他们都曾在综合医院就诊过。我们记录了他们的临床特征,并进行了头痛影响测试-6(HIT-6)和失眠严重程度指数(ISI)评估。我们还通过 Mini 国际神经精神访谈-Plus 第五版(MINI)访谈来识别重性抑郁障碍(MDD)、广泛性焦虑障碍(GAD)和自杀意念。我们比较了 TTH 患者和健康对照组之间的自杀意念发生率。还确定了自杀意念的主要危险因素。我们从五家综合医院共招募了 332 名 TTH 患者和数量相同的健康对照组。82 名(24.7%)TTH 患者存在自杀意念。TTH 患者的自杀意念发生率明显高于对照组。此外,慢性 TTH(CTTH)患者的自杀意念发生率高于对照组。自杀意念的主要危险因素包括 MDD、GAD、教育程度低、失眠、TTH 的慢性病程和颅周压痛。自杀意念或尝试似乎是 TTH 的一个常见特征。因此,识别与 TTH 患者自杀意念相关的危险因素很重要,这可能有助于降低自杀意念的发生率。

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