Department of Occupational and Environmental Health Sciences, School of Public Health, Peking University, Beijing 100191, China.
Department of Building Science, School of Architecture, Tsinghua University, Beijing 100084, China.
Environ Pollut. 2019 Nov;254(Pt B):113054. doi: 10.1016/j.envpol.2019.113054. Epub 2019 Aug 24.
Indoor air pollution is associated with numerous adverse health outcomes. Air purifiers are widely used to reduce indoor air pollutants. Ionization air purifiers are becoming increasingly popular for their low power consumption and noise, yet its health effects remain unclear. This randomized, double-blind crossover study is conducted to explore the cardiorespiratory effects of ionization air purification among 44 children in Beijing. Real or sham purification was performed in classrooms for 5 weekdays. Size-fractionated particulate matter (PM), black carbon (BC), ozone (O), and negative air ions (NAI) were monitored, and cardiorespiratory functions were measured. Mixed-effect models were used to establish associations between exposures and health parameters. Real purification significantly decreased PM and BC, e.g. PM, PM, PM and BC were decreased by 48%, 44%, 34% and 50%, respectively. O levels were unchanged, while NAI was increased from 12 cm to 12,997 cm. Real purification was associated with a 4.4% increase in forced exhaled volume in 1 s (FEV) and a 14.7% decrease in fractional exhaled nitrogen oxide (FeNO). However, heart rate variability (HRV) was altered negatively. Interaction effects of NAI and PM were observed only on HRV, and alterations in HRV were greater with high NAI. Ionization air purifier could bring substantial respiratory benefits, however, the potential negative effects on HRV need further investigation.
室内空气污染与许多不良健康后果有关。空气净化器被广泛用于减少室内空气污染物。电离空气净化器因其低功耗和低噪音而越来越受欢迎，但它对健康的影响仍不清楚。本随机、双盲交叉研究旨在探讨北京 44 名儿童使用电离空气净化的心肺呼吸效应。在教室中进行了 5 个工作日的真实或模拟净化。监测了分粒径颗粒物（PM）、黑碳（BC）、臭氧（O）和空气负离子（NAI），并测量了心肺功能。混合效应模型用于建立暴露与健康参数之间的关联。真实净化显著降低了 PM 和 BC，例如，PM、PM、PM 和 BC 分别降低了 48%、44%、34%和 50%。O 水平不变，而 NAI 从 12cm 增加到 12,997cm。真实净化与用力呼气量 1 秒（FEV）增加 4.4%和呼气一氧化氮分数（FeNO）减少 14.7%有关。然而，心率变异性（HRV）受到负面影响。仅在 HRV 上观察到 NAI 和 PM 的交互作用，而高 NAI 时 HRV 的变化更大。电离空气净化器可以带来显著的呼吸益处，但对 HRV 的潜在负面影响需要进一步研究。
