Goseki N, Shimojyu K, Nobusawa S, yamazaki S, Takiguchi T, Yoshino K, Endo M
First Department of Surgery, School of Medicine, Tokyo Medical and Dental University, Japan.
Nihon Geka Gakkai Zasshi. 1988 Sep;89(9):1363-6.
We studied the effect of early postoperative enteral hyperalimentation on the nutritional state and hormones in digestive organs in twenty patients who underwent resection of thoracic esophageal carcinoma and reconstruction of new esophagus. Following results were obtained. 1. Although enteral hyperalimentation was started in the early postoperative period (postoperative 3 day), the incidence of complications including diarrhea was decreased dramatically and satisfactory nutritional effect was obtained due to the development of many excellent chemically defined enteral nutrients. 2. Gut hormones including CCK showed the same response as in the preoperative period to the loading of enteral nutrients. And that, it is suggested that the response of CCK is affected by the lipid content in the nutrients and that this response was effective to prevent the postoperative biliary stasis. 3. Enteral nutrition made it possible to self-regulate water absorption from digestive organs, to control body fluid volume and to prevent over hydration or hypovolemia to comparison with parenteral nutrition.
我们对20例行胸段食管癌切除及新食管重建术的患者，研究了术后早期肠内高营养对营养状况及消化器官激素的影响。获得了以下结果。1. 尽管术后早期（术后第3天）即开始肠内高营养，但由于许多优质的化学限定肠内营养制剂的出现，包括腹泻在内的并发症发生率显著降低，并获得了满意的营养效果。2. 包括胆囊收缩素（CCK）在内的肠激素对肠内营养负荷的反应与术前相同。并且提示，CCK的反应受营养制剂中脂质含量的影响，这种反应对预防术后胆汁淤积有效。3. 与肠外营养相比，肠内营养使消化器官能够自我调节水的吸收，控制体液量，并预防水过多或血容量不足。
