New Cell Block Method to Enhance the Cellular Yield in Mucous and/or Bloody Samples.

OBJECTIVE

Cell blocks (CBs) are used to complement cytological diagnosis and for ancillary testing. Dissatisfaction with the cellular yield of the CB is widely recognized. Various techniques have been developed to increase the diagnostic utility of CBs.

STUDY DESIGN

We invented a new CB technique to increase cellular yield and diagnostic accuracy suitable especially for mucous and/or bloody cytological samples.

RESULTS

The new CB technique is described in detail with illustrations and cases, where it increased the cellular yield and diagnostic accuracy. CBs prepared by this method are suitable also for ancillary techniques, namely immunocytochemistry.

CONCLUSIONS

The newly described method showed a better cellular yield in mucous and/or bloody cytological specimens.