Fava Agostina M, Meredith Dane, Desai Milind Y
Heart and Vascular Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk J1-5, Cleveland, OH, 44195, USA.
Curr Treat Options Cardiovasc Med. 2019 Aug 31;21(10):50. doi: 10.1007/s11936-019-0761-0.
This article reviews recent advances in echocardiographic strain imaging, particularly in its ability to prognosticate in cardiovascular outcomes and impact clinical decision making.
Strain has been proposed as a sensitive tool in detecting early ventricular dysfunction. Left ventricular global longitudinal strain (LV-GLS) detects subtle changes in myocardial function, often not quantifiable by ejection fraction alone. Thus, LV-GLS provides the opportunity for early decision-making, and the implementation of more effective treatments, improving outcomes in a variety of diseases such as valvular heart diseases, cardio-oncology, ischemic heart disease, cardiomyopathies, heart transplantation, and pericardial diseases and cardiomyopathies. Strain is a promising tool for the early detection of myocardial dysfunction in patients with preserved left ventricular ejection fraction and can prognosticate long-term outcomes.
本文回顾了超声心动图应变成像的最新进展，特别是其在预测心血管结局和影响临床决策方面的能力。
应变已被提议作为检测早期心室功能障碍的敏感工具。左心室整体纵向应变（LV-GLS）可检测心肌功能的细微变化，这些变化通常仅靠射血分数无法量化。因此，LV-GLS为早期决策以及实施更有效的治疗提供了机会，从而改善多种疾病（如心脏瓣膜病、心脏肿瘤学、缺血性心脏病、心肌病、心脏移植以及心包疾病和心肌病）的预后。应变是检测左心室射血分数保留患者心肌功能障碍的一种有前景的工具，并且可以预测长期结局。
