Department of Orthopaedics and Trauma, The Royal Infirmary of Edinburgh, Edinburgh, UK.
Department of Orthopaedics, Freeman Hospital, Newcastle upon Tyne, UK.
Bone Joint J. 2019 Sep;101-B(9):1063-1070. doi: 10.1302/0301-620X.101B9.BJJ-2018-1658.R1.
The primary aim of the study was to perform an analysis to identify the cost per quality-adjusted life-year (QALY) of robot-assisted unicompartmental knee arthroplasty (rUKA) relative to manual total knee arthroplasty (TKA) and unicompartmental knee arthroplasty (UKA) for patients with isolated medial compartment osteoarthritis (OA) of the knee. Secondary aims were to assess how case volume and length of hospital stay influenced the relative cost per QALY.
A Markov decision analysis was performed, using known parameters for costs, outcomes, implant survival, and mortality, to assess the cost-effectiveness of rUKA relative to manual TKA and UKA for patients with isolated medial compartment OA of the knee with a mean age of 65 years. The influence of case volume and shorter hospital stay were assessed.
Using a model with an annual case volume of 100 patients, the cost per QALY of rUKA was £1395 and £1170 relative to TKA and UKA, respectively. The cost per QALY was influenced by case volume: a low-volume centre performing ten cases per year would achieve a cost per QALY of £7170 and £8604 relative to TKA and UKA. For a high-volume centre performing 200 rUKAs per year with a mean two-day length of stay, the cost per QALY would be £648; if performed as day-cases, the cost would be reduced to £364 relative to TKA. For a high-volume centre performing 200 rUKAs per year with a shorter length of stay of one day relative to manual UKA, the cost per QALY would be £574.
rUKA is a cost-effective alternative to manual TKA and UKA for patients with isolated medial compartment OA of the knee. The cost per QALY of rUKA decreased with reducing length of hospital stay and with increasing case volume, compared with TKA and UKA. Cite this article: 2019;101-B:1063-1070.
本研究的主要目的是进行分析,以确定机器人辅助单髁膝关节置换术(rUKA)相对于人工全膝关节置换术(TKA)和单髁膝关节置换术(UKA)治疗膝关节内侧间室骨关节炎(OA)患者的每质量调整生命年(QALY)成本。次要目的是评估病例量和住院时间长短如何影响相对每 QALY 成本。
使用已知的成本、结果、植入物存活率和死亡率参数,进行了马尔可夫决策分析,以评估 rUKA 相对于 TKA 和 UKA 治疗膝关节内侧间室 OA 且平均年龄为 65 岁的患者的成本效益。评估了病例量和较短住院时间的影响。
使用每年 100 例患者的模型,rUKA 的每 QALY 成本分别为 1395 英镑和 1170 英镑,相对于 TKA 和 UKA。每 QALY 的成本受病例量影响:每年进行 10 例手术的低容量中心将实现相对于 TKA 和 UKA 的每 QALY 成本分别为 7170 英镑和 8604 英镑。对于每年进行 200 例 rUKA 且平均住院时间为两天的高容量中心,每 QALY 的成本将为 648 英镑;如果作为日间手术进行,则相对于 TKA,成本将降低至 364 英镑。对于每年进行 200 例 rUKA 且与人工 UKA 相比住院时间缩短一天的高容量中心,每 QALY 的成本将为 574 英镑。
rUKA 是治疗膝关节内侧间室 OA 患者的一种具有成本效益的 TKA 和 UKA 替代方案。与 TKA 和 UKA 相比,rUKA 的每 QALY 成本随着住院时间的缩短和病例量的增加而降低。