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当前患者报告的结局指标是否适用于评估单髁膝关节置换术?

Are Current Patient-Reported Outcome Measures Fit for Purpose to Evaluate Unicompartmental Knee Arthroplasty?

作者信息

Bayram John M, Clement Nicholas D, Hall Andrew J, Walmsley Phil, Clarke Jon V

机构信息

Department of Orthopaedics, Golden Jubilee University National Hospital, Glasgow G81 4DY, UK.

Edinburgh Orthopaedics, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, UK.

出版信息

J Clin Med. 2025 Jan 2;14(1):203. doi: 10.3390/jcm14010203.

Abstract

The optimal procedure for isolated end-stage medial compartment knee osteoarthritis (OA) remains uncertain, with debate persisting between unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA). The aim of this narrative review is to evaluate current outcome measures in knee arthroplasty (KA) and explore how evolving patient populations and technological advancements may necessitate the use of different patient-reported outcome measures (PROMs) for evaluating UKA. While UKA offers potential advantages over TKA in early pain relief and functional outcomes, most randomised control trials using traditional PROMs have failed to show definitive superiority. The recent introduction of robotic assistance may have further enhanced the benefits of UKA. However, it remains uncertain whether the advantages outweigh the higher revision rates associated with UKA. Although traditional PROMs, such as the Oxford Knee Score or Knee Injury and Osteoarthritis Outcome Score, were designed for the KA population of 30 years ago, they continue to be employed today. The current KA population, particularly those undergoing UKA, are typically younger, physically fitter, and have higher functional demands than those for whom traditional PROMs were originally designed. As a result, these PROMs are now limited by ceiling effects. High-performance PROMs, such as the Forgotten Joint Score-12 or the metabolic equivalent of task score, have recently been utilised for high-demand patients and do not have postoperative ceiling effects. Return to work and sport are also important outcomes that are often overlooked for younger, high-demand patients. Future studies should aim to define the differences between UKA and TKA populations, identify patient factors that predict UKA success, and validate high-performance PROMs for UKA. This will provide deeper insights into the functional benefits of UKA and TKA, enabling patients and surgeons to make more informed decisions regarding implant selection.

摘要

对于单纯终末期内侧间室膝关节骨关节炎(OA)的最佳治疗方案仍不明确,单髁膝关节置换术(UKA)和全膝关节置换术(TKA)之间的争论依然存在。本叙述性综述的目的是评估膝关节置换术(KA)中当前的疗效评估指标,并探讨不断变化的患者群体和技术进步如何可能需要使用不同的患者报告结局指标(PROMs)来评估UKA。虽然UKA在早期疼痛缓解和功能结局方面比TKA具有潜在优势,但大多数使用传统PROMs的随机对照试验未能显示出明确的优越性。最近引入的机器人辅助可能进一步增强了UKA的优势。然而,其优势是否超过与UKA相关的更高翻修率仍不确定。尽管传统的PROMs,如牛津膝关节评分或膝关节损伤和骨关节炎结局评分,是为30年前的KA患者群体设计的,但至今仍在使用。当前的KA患者群体,尤其是接受UKA的患者,通常比传统PROMs最初设计所针对的患者更年轻、身体更健康,功能需求更高。因此,这些PROMs现在受到天花板效应的限制。高性能的PROMs,如遗忘关节评分-12或代谢当量任务评分,最近已用于高需求患者,且没有术后天花板效应。重返工作和运动也是重要的结局,但对于年轻的高需求患者来说往往被忽视。未来的研究应旨在明确UKA和TKA患者群体之间的差异,确定预测UKA成功的患者因素,并验证用于UKA的高性能PROMs。这将更深入地了解UKA和TKA的功能益处,使患者和外科医生能够在植入物选择方面做出更明智的决策。

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