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Three new drugs for multiple myeloma.三种用于治疗多发性骨髓瘤的新药。
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[Bispecific antibodies in multiple myeloma].[多发性骨髓瘤中的双特异性抗体]
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ImmunoPET in Multiple Myeloma-What? So What? Now What?多发性骨髓瘤中的免疫正电子发射断层扫描——是什么？那又怎样？现在该怎么办？
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1
Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy.肿瘤靶向 4-1BB 激动剂与 T 细胞双特异性抗体联合作为现货治疗。
Sci Transl Med. 2019 Jun 12;11(496). doi: 10.1126/scitranslmed.aav5989.
2
Twists and turns to translating 4-1BB cancer immunotherapy.4-1BB 癌症免疫疗法的曲折历程。
Sci Transl Med. 2019 Jun 12;11(496). doi: 10.1126/scitranslmed.aax4738.
3
Multifunctional Natural Killer Cell Engagers Targeting NKp46 Trigger Protective Tumor Immunity.多功能自然杀伤细胞衔接器靶向 NKp46 触发保护性肿瘤免疫。
Cell. 2019 Jun 13;177(7):1701-1713.e16. doi: 10.1016/j.cell.2019.04.041. Epub 2019 May 30.
4
Daratumumab in combination with urelumab to potentiate anti-myeloma activity in lymphocyte-deficient mice reconstituted with human NK cells.达雷妥尤单抗联合urelumab增强用人自然杀伤细胞重建的淋巴细胞缺陷小鼠的抗骨髓瘤活性。
Oncoimmunology. 2019 Apr 13;8(7):1599636. doi: 10.1080/2162402X.2019.1599636. eCollection 2019.
5
Mechanism of Action of a New Anti-CD38 Antibody: Enhancing Myeloma Immunotherapy.新型抗 CD38 抗体的作用机制：增强骨髓瘤免疫疗法。
Clin Cancer Res. 2019 May 15;25(10):2946-2948. doi: 10.1158/1078-0432.CCR-19-0260. Epub 2019 Mar 7.
6
Immunotherapy in myeloma: how far have we come?骨髓瘤的免疫疗法：我们已经取得了多大进展？
Ther Adv Hematol. 2019 Jan 18;10:2040620718822660. doi: 10.1177/2040620718822660. eCollection 2019.
7
Novel Agents in Multiple Myeloma.多发性骨髓瘤的新型药物。
Cancer J. 2019 Jan/Feb;25(1):45-53. doi: 10.1097/PPO.0000000000000355.
8
The Mechanism of Action of the Anti-CD38 Monoclonal Antibody Isatuximab in Multiple Myeloma.抗 CD38 单克隆抗体伊沙妥昔单抗在多发性骨髓瘤中的作用机制。
Clin Cancer Res. 2019 May 15;25(10):3176-3187. doi: 10.1158/1078-0432.CCR-18-1597. Epub 2019 Jan 28.
9
Current use of monoclonal antibodies in the treatment of multiple myeloma.目前在多发性骨髓瘤治疗中使用的单克隆抗体。
Br J Haematol. 2018 May;181(4):447-459. doi: 10.1111/bjh.15121. Epub 2018 Apr 25.
10
CD38 antibodies in multiple myeloma: back to the future.多发性骨髓瘤中的 CD38 抗体：回到未来。
Blood. 2018 Jan 4;131(1):13-29. doi: 10.1182/blood-2017-06-740944. Epub 2017 Nov 8.

Editorial: Immunotherapy in Multiple Myeloma.

作者信息

Giuliani Nicola, Malavasi Fabio

机构信息

Department of Medicine and Surgery, University of Parma, Parma, Italy.

U.O. di Ematologia e Centro Trapianti Midollo Osseo, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.

出版信息

Front Immunol. 2019 Aug 14;10:1945. doi: 10.3389/fimmu.2019.01945. eCollection 2019.

DOI:10.3389/fimmu.2019.01945
PMID:31475006
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6702966/
Abstract
摘要