Renaissance Center for Plastic Surgery, Shavertown, Pennsylvania.
Cook Biotech Incorporated, West Lafayette, Indiana.
Int Wound J. 2019 Oct;16(5):1222-1229. doi: 10.1111/iwj.13208. Epub 2019 Sep 2.
Managing acute wounds with soft tissue loss can be very challenging for both patients and physicians. Successful wound healing depends on several factors including exudate control, prevention of infection, and moisture balance. In this case series, we describe a novel combination treatment method utilising small intestinal submucosa wound matrix (SISWM) with the bolster technique as a way of assisting the integration of collagen-based wound treatment products into the base of complex wounds with the intent of restoring a dysfunctional extracellular matrix. In case 1, a 44-year-old female presented with an acute wound resulting from a spider bite to the posterior aspect of the right knee. In case 2, a 12-year-old male sustained multiple injuries to his right foot from an all-terrain vehicle accident. In case 3, an 80-year-old female on anticoagulants sustained an avulsion injury to her left lower leg. In case 4, a 41-year-old female sustained a severe complex avulsion injury to the dorsal left forearm sustained from a dog bite. All patients were successfully treated with SISWM and the bolster technique, and their wounds healed completely within 6 weeks. The bolster technique, when combined with an SISWM, is a novel method designed to enable the SISWM to impart its wound healing properties to these complex traumatic wounds. This case series presents treating clinicians with a different treatment methodology to assist the patient in achieving a successful outcome.
处理伴有软组织缺损的急性伤口对患者和医生来说都是极具挑战性的。成功的伤口愈合取决于多个因素，包括渗出物控制、预防感染和保持水分平衡。在本病例系列中，我们描述了一种新颖的联合治疗方法，即将小肠黏膜下层创伤基质（SISWM）与支撑技术结合使用，以帮助将基于胶原蛋白的伤口治疗产品整合到复杂伤口的底部，目的是恢复功能失调的细胞外基质。在病例 1 中，一名 44 岁的女性因被蜘蛛咬伤右膝后侧而出现急性伤口。在病例 2 中，一名 12 岁的男性因全地形车事故导致右脚多处受伤。在病例 3 中，一名 80 岁的女性因服用抗凝药物而导致左小腿撕脱伤。在病例 4 中，一名 41 岁的女性因被狗咬伤导致左手背严重复杂撕脱伤。所有患者均成功接受 SISWM 和支撑技术治疗，其伤口在 6 周内完全愈合。支撑技术与 SISWM 联合使用是一种新颖的方法，旨在使 SISWM 将其伤口愈合特性传递给这些复杂的创伤性伤口。本病例系列为治疗临床医生提供了一种不同的治疗方法，以帮助患者获得成功的结果。
