Leerssen Eeke C M, Tak Ramon O, Breur Johannes M P J
Department of Paediatric Cardiology, University Medical Centre/Wilhelmina Children's Hospital, Utrecht, the Netherlands.
Cardiol Young. 2019 Oct;29(10):1300-1301. doi: 10.1017/S1047951119001938. Epub 2019 Sep 2.
A female neonate with in utero selective serotonin reuptake inhibitor exposure presented with bradycardia shortly after birth. Electrocardiography showed severe QT prolongation and second-degree atrioventricular block. Over time QT-times spontaneously normalised and genetic testing did not show mutations associated with long QT syndrome making maternal selective serotonin reuptake inhibitor usage the most likely explanation for the observed severe transient neonatal QT prolongation.
一名在子宫内暴露于选择性5-羟色胺再摄取抑制剂的女新生儿在出生后不久出现心动过缓。心电图显示严重QT间期延长和二度房室传导阻滞。随着时间推移，QT间期自行恢复正常，基因检测未显示与长QT综合征相关的突变，这使得母亲使用选择性5-羟色胺再摄取抑制剂最有可能是观察到的严重短暂性新生儿QT间期延长的原因。
