[帕罗西汀治疗后的心电图变化。3例病例报告]
[ECG changes after paroxetine. 3 case reports].
作者信息
Erfurth A, Loew M, Dobmeier P, Wendler G
机构信息
Psychiatrische Klinik der Universität, München.
出版信息
Nervenarzt. 1998 Jul;69(7):629-31. doi: 10.1007/s001150050321.
PMID:9715482
Abstract
Selective serotonin reuptake inhibitors (SSRI) are known to exhibit far less cardiac side effects than tricyclic antidepressants. We report three cases in which the SSRI, paroxetine, induced clinically relevant ECG changes in patients with high risk profile. In two cases an increase in QTc time was observed, severe bradycardia was also observed twice.
摘要
已知选择性5-羟色胺再摄取抑制剂（SSRI）的心脏副作用远少于三环类抗抑郁药。我们报告了3例使用SSRI帕罗西汀后，在高危患者中诱发具有临床意义的心电图改变的病例。其中2例观察到QTc时间延长，还有2例出现严重心动过缓。
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