Badarinza Maria, Serban Oana, Maghear Lavinia, Bocsa Corina, Micu Mihaela, Porojan Mihai Dumitru, Chis Bogdan Augustin, Albu Adriana, Fodor Daniela
2nd Internal Medicine Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Rheumatology Division, Rehabilitation Clinical Hospital, Cluj-Napoca, Romania.
Med Ultrason. 2019 Aug 31;21(3):257-264. doi: 10.11152/mu-2164.
To evaluate the ultrasound (US) modifications [grey scale, Doppler, 2D-share wave elastography (2D-SWE)] ofsalivary (parotid and submandibular) and lacrimal glands in healthy people and patients with diabetes mellitus and/or obesity, with or without sialosis.
We evaluated 170 patients (1020 glands, 1700 grey scale and Doppler images), split in two groups (group 1- healthy people, group 2- obese and/or diabetes patients, with or without sialosis). For each patient we assessed the parotid, submandibular and lacrimal glands in grey scale US (echogenicity, homogeneity, glandular contour, posterior border, lymph nodes), color Doppler US and 2D-SWE. All images were analyzed by two examiners blinded to each other or to patients.
The interobserver agreement was strong or moderate for all parameters. In group 2, the salivary glands had increased echogenicity, homogeneous aspect and invisible posterior border (all p<0.001). There was no significant variation of elasticity modulus in the groups analyzed (5.46±1.57 vs 5.67±1.81 in parotid, 8.63±1.84 vs 8.55±1.94 in submandibular and 9.47±2.1 vs 9.53±2.23 in lacrimal glands, all p>0.05) or according to the body mass index (BMI), sex, patient age, the aspect in grey scale/Doppler US or the presence of sialosis (all p>0.05).
The main US differences between healthy people and patients with diabetes mellitus and/or obesity are suggested by the echogenicity, homogeneity, posterior border and the size of glandular area. No significant differences of elasticity modulus were found between the analyzed groups or related to BMI, sex, patient age or other grey scale/Doppler US items analyzed.
评估超声（US）对健康人群以及患有糖尿病和/或肥胖症（无论有无涎腺肿大）患者的唾液腺（腮腺和颌下腺）及泪腺的改变[灰阶、多普勒、二维剪切波弹性成像（2D-SWE）]。
我们评估了170例患者（1020个腺体，1700幅灰阶和多普勒图像），分为两组（第1组-健康人群，第2组-肥胖和/或糖尿病患者，无论有无涎腺肿大）。对每位患者的腮腺、颌下腺和泪腺进行灰阶超声检查（回声性、均匀性、腺体轮廓、后缘、淋巴结）、彩色多普勒超声检查和二维剪切波弹性成像检查。所有图像由两名彼此或对患者不知情的检查人员进行分析。
所有参数的观察者间一致性为强或中等。在第2组中，唾液腺回声性增强、呈均匀外观且后缘不可见（所有p<0.001）。在分析的各组中，弹性模量无显著差异（腮腺为5.46±1.57对5.67±1.81，颌下腺为8.63±1.84对8.55±
