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小儿阻塞性睡眠呼吸暂停筛查问卷与术后结果:一项前瞻性观察研究。

Pediatric obstructive sleep apnea screening questionnaire and post-operative outcomes: A prospective observational study.

作者信息

Raman Vidya T, Geyer Emily, Miller Rebecca, Tumin Dmitry, Splaingard Mark, Jatana Kris R, Tobias Joseph D

机构信息

Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, USA; Department of Anesthesiology & Pain Medicine, The Ohio State University, Columbus, USA.

Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, USA.

出版信息

Int J Pediatr Otorhinolaryngol. 2019 Dec;127:109661. doi: 10.1016/j.ijporl.2019.109661. Epub 2019 Aug 28.

Abstract

INTRODUCTION

Obstructive Sleep Apnea (OSA) and Sleep Disordered Breathing (SDB) in children tend to be a more complex and multifactorial disease than in adults. Although adult screening tools, such as the STOP-BANG questionnaire, their application limited in pediatrics. We used our previously described 6-point questionnaire to identify OSA in children and evaluated its use for predicting post-operative respiratory events.

METHODS

Children from 3 to 18 years of age presenting for surgery were eligible. Exclusion criteria were emergency surgery or refusal to participate. A 6-question survey regarding symptoms of OSA/SDB was administered preoperatively. Neck circumference was measured. Height and weight were recorded from preoperative data and the body mass index (BMI) percentile obtained.

RESULTS

749 patients were enrolled in the study. 707 patients were in the final analysis (359 boys and 348 girls, mean age 12 ± 4 years). The median 6-item questionnaire score was 1 (interquartile range: 0, 2) and 186 (26%) scored ≥ 2 of 6 points. Children with predicted OSA (yes on ≥ 2 questions) were more likely than without predicted OSA to require supplemental oxygen in the PACU (24% vs. 17%; 95% confidence interval [CI] of difference: -0.3%, 13%; p = 0.049). Amongst 681 patients with available data on Post Anesthesia Care Unit (PACU) length of stay (LOS), prolonged LOS (>1 h) was not more likely among children with predicted OSA (42%) compared to those without predicted OSA (39%; 95% CI of difference: -5%, 11%; p = 0.479). Outcomes assessed after PACU discharge noted no differences. Specifically, overnight hospital stay was required in 33% of patients with predicted OSA as compared to 29% of those without (95% CI of difference: -4%, 11%; p = 0.399). On POD 0, supplemental oxygen was used on the inpatient ward for 6% of patients with predicted OSA compared to 4% of patients without predicted OSA (95% CI of difference: -2%, 6%; p = 0.272).

CONCLUSION

The incidence of OSA/SDB is under-appreciated in children presenting for non-otolaryngological surgical procedures. Although patients judged to have OSA on the 6-item question may need for supplemental oxygen longer in the PACU, no other outcomes differences were noted.

摘要

引言

儿童阻塞性睡眠呼吸暂停(OSA)和睡眠呼吸障碍(SDB)往往比成人更为复杂且具有多因素性。尽管有成人筛查工具,如STOP-BANG问卷,但其在儿科的应用有限。我们使用之前描述的6分问卷来识别儿童OSA,并评估其用于预测术后呼吸事件的效用。

方法

3至18岁接受手术的儿童符合条件。排除标准为急诊手术或拒绝参与。术前进行了一项关于OSA/SDB症状的6个问题的调查。测量了颈围。从术前数据记录身高和体重,并获得体重指数(BMI)百分位数。

结果

749名患者纳入研究。707名患者进行最终分析(359名男孩和348名女孩,平均年龄12±4岁)。6项问卷得分中位数为1(四分位间距:0,2),186名(26%)得分≥6分中的2分。预测有OSA(6个问题中≥2个回答为是)的儿童比预测无OSA的儿童在麻醉后恢复室(PACU)更有可能需要补充氧气(24%对17%;差异的95%置信区间[CI]:-0.3%,13%;p = 0.049)。在681名有麻醉后护理单元(PACU)住院时间(LOS)可用数据的患者中,预测有OSA的儿童(42%)与预测无OSA的儿童相比,延长住院时间(>1小时)的可能性并不更高(39%;差异的95%CI:-5%,11%;p = 0.479)。PACU出院后评估的结果未发现差异。具体而言,预测有OSA的患者中有33%需要过夜住院,而预测无OSA的患者中这一比例为29%(差异的95%CI:-4%,11%;p = 0.399)。在术后第0天,预测有OSA的患者中有6%在住院病房使用补充氧气,而预测无OSA的患者中这一比例为4%(差异的95%CI:-2%,6%;p = 0.272)。

结论

在接受非耳鼻喉科手术的儿童中,OSA/SDB的发生率未得到充分认识。尽管在6项问题中被判定有OSA的患者在PACU可能需要更长时间的补充氧气,但未发现其他结果差异。

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