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筛查问卷和多导睡眠图对预测儿童术后结局的效用。

Utility of screening questionnaire and polysomnography to predict postoperative outcomes in children.

作者信息

Kako Hiromi, Tripi Jennifer, Walia Hina, Tumin Dmitry, Splaingard Mark, Jatana Kris R, Tobias Joseph D, Raman Vidya T

机构信息

Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, USA; Department of Anesthesiology & Pain Medicine, The Ohio State University, Columbus, USA.

The University of Toledo College of Medicine and Life Sciences, Toledo, USA.

出版信息

Int J Pediatr Otorhinolaryngol. 2017 Nov;102:71-75. doi: 10.1016/j.ijporl.2017.09.006. Epub 2017 Sep 14.

Abstract

INTRODUCTION

The prevalence of pediatric obstructive sleep apnea (OSA) has increased concurrently with the increasing prevalence of obesity. We have previously validated a short questionnaire predicting the occurrence of OSA on polysomnography (PSG). This follow-up study assessed the utility of the questionnaire in predicting postoperative outcomes.

METHODS

Children undergoing surgery and completing a sleep study were prospectively screened for OSA using a short questionnaire. Procedures within 1 year of PSG were included in the analysis. Questionnaires were scored according to a cutoff previously deemed optimal for predicting OSA (apnea-hypopnea index ≥ 5) on the sleep study. Postoperative outcomes included prolonged (>60 min) length of stay (LOS) in the post-anesthesia care unit (PACU) and oxygen requirement in the PACU.

RESULTS

The study cohort included 185 patients (100/85 male/female) age 8 ± 4 years, undergoing adenotonsillectomy (n = 109), other ear, nose, and throat (ENT) procedures (n = 18), or non-ENT procedures (n = 58). There were 45 patients with OSA documented by PSG and 122 patients identified as likely to have OSA according to questionnaire responses (89% sensitivity, 41% specificity). PACU LOS was prolonged in 55/181 (30%) cases and supplemental oxygen was used in the PACU in 29/181 (16%) cases. In separate multivariable models, supplemental oxygen use in the PACU was more common if a patient scored ≥2/6 points on the short questionnaire scale (OR = 5.0; 95% CI: 1.3, 19.9; p = 0.023) or if the patient was diagnosed with OSA on PSG (OR = 4.6; 95% CI: 1.6, 13.5; p = 0.005). Neither OSA on PSG nor questionnaire score ≥2/6 were associated with prolonged PACU stay.

CONCLUSION

Both OSA diagnosis based on the AHI and the questionnaire scale achieved comparable predictive value for the need for oxygen use in the PACU. The utility of the questionnaire in predicting rare adverse events (e.g., unplanned admission or rapid response team activation) remains to be determined. Our preliminary results support using a brief questionnaire scale for preoperative risk stratification among children with suspected OSA who have not had a formal sleep study.

摘要

引言

小儿阻塞性睡眠呼吸暂停(OSA)的患病率随着肥胖患病率的增加而同时上升。我们之前已经验证了一份简短问卷可预测多导睡眠图(PSG)上OSA的发生情况。这项随访研究评估了该问卷在预测术后结果方面的效用。

方法

对接受手术并完成睡眠研究的儿童使用一份简短问卷进行前瞻性OSA筛查。PSG后1年内的手术纳入分析。问卷根据之前认为对预测睡眠研究中OSA(呼吸暂停低通气指数≥5)最适宜的临界值进行评分。术后结果包括在麻醉后护理单元(PACU)停留时间延长(>60分钟)以及PACU内的氧气需求。

结果

研究队列包括185例患者(男100例/女85例),年龄8±4岁,接受腺样体扁桃体切除术(n = 109)、其他耳鼻喉(ENT)手术(n = 18)或非ENT手术(n = 58)。PSG记录有45例OSA患者,根据问卷回答确定有122例患者可能患有OSA(敏感性89%,特异性41%)。181例中有55例(30%)在PACU的停留时间延长,181例中有29例(16%)在PACU使用了补充氧气。在单独的多变量模型中,如果患者在简短问卷量表上得分≥2/6分(比值比[OR]=5.0;95%置信区间[CI]:1.3,19.9;p = 0.023)或患者在PSG上被诊断为OSA(OR = 4.6;95% CI:1.6,13.5;p = 0.005),则在PACU使用补充氧气更为常见。PSG上的OSA和问卷得分≥2/6均与PACU停留时间延长无关。

结论

基于呼吸暂停低通气指数(AHI)的OSA诊断和问卷量表在预测PACU内氧气使用需求方面具有相当的预测价值。该问卷在预测罕见不良事件(如意外入院或快速反应团队启动)方面的效用仍有待确定。我们的初步结果支持对未进行正式睡眠研究的疑似OSA儿童在术前使用简短问卷量表进行风险分层。

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