早期乳腺癌的治疗进展。
Update on the management of early-stage breast cancer.
机构信息
MD, MS, Jordanian Board of General Surgery (JBGS), Breast Surgery Fellow, Westmead Breast Cancer Institute, Westmead Hospital, NSW; Clinical Lecturer, School of Medicine/Clinical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan.
FRACGP, FASBP, PhD, Clinical Associate Professor, Breast Physician, Northern and Westmead Clinical Schools, School of Medicine, Faculty of Medicine and Health, University of Sydney, NSW.
出版信息
Aust J Gen Pract. 2019 Sep;48(9):604-608. doi: 10.31128/AJGP-03-19-4891.
BACKGROUND
Breast cancer affects one in eight Australian women. While surgery, chemotherapy, radiotherapy and endocrine therapy are still the main treatments, there have been changes in the sequencing of treatment and advances in each therapy. The general practitioner (GP) is involved at each stage of the patient's journey.
OBJECTIVE
This article discusses the current approach to the management of early breast cancer. It focuses on changes in recent years and discusses the role of the GP in supporting women in their decision-making and treatment.
DISCUSSION
Key changes include the increasing use of neoadjuvant chemotherapy, the development of advanced oncoplastic surgery and breast reconstruction techniques, the use of gene expression profiling and the recommendation for extended adjuvant endocrine therapy for up to 10 years.
背景
乳腺癌影响每 8 位澳大利亚女性中的 1 位。虽然手术、化疗、放疗和内分泌治疗仍然是主要治疗方法，但治疗的顺序已经发生了变化，每种治疗方法都有了进展。全科医生（GP）在患者治疗的各个阶段都有参与。
目的
本文讨论了早期乳腺癌的当前治疗方法。它重点讨论了近年来的变化，并讨论了全科医生在支持女性做出决策和治疗方面的作用。
讨论
主要变化包括新辅助化疗的使用增加、先进的肿瘤整形手术和乳房重建技术的发展、基因表达谱的使用以及建议延长辅助内分泌治疗长达 10 年。
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