MD, MS, Assistant Professor of Surgery, Division of Surgical Oncology, NYU Langone Health, New York, NY, USA.
MD, Conjoint Medical Director, Melanoma Institute Australia, University of Sydney, Sydney, NSW; Clinical Professor, Discipline of Pathology, Faculty of Medicine and Health, University of Sydney, Sydney, NSW; Senior Staff Specialist in Anatomical Pathology, Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, NSW.
Aust J Gen Pract. 2019 Sep;48(9):621-624. doi: 10.31128/AJGP-04-19-48952.
As a result of the rapidly changing hormonal milieu, changing or newly discovered pigmented skin lesions during pregnancy can be diagnostically challenging. It is important for GPs to be aware of the effect of gestational changes on pigment production and features that should raise concern.
The aim of this article is to provide an understanding of common changes that may occur in pigmented lesions during pregnancy, features that are of concern and the management of suspected melanoma in pregnant women.
In pregnant women, changing naevi should be evaluated using conventional ABCDE melanoma diagnostic criteria, and suspicious lesions should not be attributed solely to a change in the hormonal milieu. In this population, diagnosed melanoma is probably best treated at a specialist centre.
由于激素环境的迅速变化，怀孕期间出现的变化或新发现的色素性皮肤病变可能具有诊断挑战性。全科医生应该意识到妊娠变化对色素产生和应引起关注的特征的影响。
本文旨在了解怀孕期间色素性病变可能发生的常见变化、值得关注的特征以及疑似孕妇黑色素瘤的处理方法。
在孕妇中，应使用传统的 ABCDE 黑色素瘤诊断标准评估变化的痣，并且不应仅将可疑病变归因于激素环境的变化。在这一人群中，诊断出的黑色素瘤可能最好在专门中心进行治疗。
