Department of Hepatobiliary Surgery, The Affiliated Hospital of Southwest Medical University, No. 25 Taiping Street, Jiangyang District, Luzhou, 646000, Sichuan Province, China.
Department of Nephrology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, Sichuan Province, China.
BMC Med Imaging. 2019 Sep 2;19(1):77. doi: 10.1186/s12880-019-0376-7.
The value of magnetic resonance imaging (MRI), contrast-enhanced ultrasound (CEUS), and the combination of CEUS and MRI (CCWM) for the diagnosis of periampullary space-occupying lesions (PSOL) was investigated.
A total of 102 patients diagnosed with PSOLs by surgery or biopsy were recruited retrospectively. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of MRI, CEUS, and CCWM were analyzed.
MRI, CEUS, and CCWM allowed for the accurate detection of 91.17, 92.15, and 99.01% of PSOLs, respectively. The specificity, PPV, and accuracy of CCWM were significantly different from MRI and CEUS (p < 0.05). However, there the sensitivity and NPV were not significantly different among the three diagnostic technologies. In addition, the specificity, PPV, and accuracy were not significantly different between MRI and CEUS (all p > 0.05).
CCWM is valuable for differentiating benign and malignant PSOL, which provides important guiding significances for the clinic.
本研究旨在探讨磁共振成像（MRI）、对比增强超声（CEUS）及 CEUS 与 MRI 联合（CCWM）对壶腹周围占位性病变（PSOL）的诊断价值。
回顾性分析了 102 例经手术或活检诊断为 PSOL 的患者。分析 MRI、CEUS 和 CCWM 的灵敏度、特异度、阳性预测值（PPV）、阴性预测值（NPV）和准确率。
MRI、CEUS 和 CCWM 对 PSOL 的检出率分别为 91.17%、92.15%和 99.01%。CCWM 的特异度、PPV 和准确率与 MRI 和 CEUS 相比差异有统计学意义（p<0.05）。然而，三种诊断技术之间的敏感度和 NPV 差异无统计学意义。此外，MRI 和 CEUS 的特异度、PPV 和准确率差异无统计学意义（均 p>0.05）。
CCWM 对鉴别壶腹周围 PSOL 的良恶性有价值，可为临床提供重要指导意义。
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