Silva C L, Faccioli L H, Rocha G M
Departamento de Parasitologia, Microbiologia e Immunologia, Faculdade de Medicina de Ribeiräo Preto, Universidade de Säo Paulo, Brasil.
Braz J Med Biol Res. 1988;21(3):489-92.
The presence of cachectin or tumor necrosis factor (TNF) associated with hypertriglyceridemia was demonstrated in the serum of patients with pulmonary tuberculosis. The hyperlipidemia that accompanies this infection may be mediated by the TNF inhibition of lipoprotein lipase activity. This sequence of events may be sufficient to explain, in part, the complex metabolic changes and emaciation observed in tuberculosis patients.
在肺结核患者的血清中证实存在与高甘油三酯血症相关的恶病质素或肿瘤坏死因子（TNF）。伴随这种感染出现的高脂血症可能是由TNF对脂蛋白脂肪酶活性的抑制作用介导的。这一系列事件可能足以部分解释在结核病患者中观察到的复杂代谢变化和消瘦现象。
