Aguadé M, Serra L
Departamento de Genètica, Facultad de Biologia, Universidad de Barcelona, Spain.
Genetica. 1987 Nov 16;75(1):3-9. doi: 10.1007/BF00056027.
Variation in Adh and alpha Gpdh-1 gene frequencies has been used to check for microdifferentiation in Spanish samples of Drosophila melanogaster inside and outside a wine cellar. Flies were collected after vintage and after overwintering respectively; within each period samples were taken on up to five consecutive days each month. Variation of gene frequencies of Adh and alpha Gpdh-1 can be considered random when samples collected each month are taken into account. When mean monthly frequencies are considered, alpha Gpdh-1 does not show any significant variation all over the year; yet, variation of the frequency of AdhS shows a cyclical pattern, its frequency being maximum at the end of the summer and minimum after overwintering. Due to the parallel change of the frequency of the inversion In(2L)t and the AdhS allele, no decision can be made whether the Adh locus itself or the inversion are responsible for the changes.
已利用乙醇脱氢酶（Adh）和α-甘油磷酸脱氢酶-1（alpha Gpdh-1）基因频率的变化，来检测酒窖内外西班牙黑腹果蝇样本中的微分化情况。果蝇分别在收获季节后和越冬后采集；在每个时期内，每月连续最多五天采集样本。当考虑每月采集的样本时，Adh和alpha Gpdh-1的基因频率变化可被视为随机的。当考虑每月平均频率时，alpha Gpdh-1全年均未显示出任何显著变化；然而，AdhS频率的变化呈现出周期性模式，其频率在夏末最高，越冬后最低。由于倒位In(2L)t和AdhS等位基因频率的平行变化，无法确定是Adh基因座本身还是倒位导致了这些变化。
