Malpica J M, Vassallo J M, Frías A, Fuentes-Bol F
Genetics. 1987 Jan;115(1):141-2. doi: 10.1093/genetics/115.1.141.
The occurrence and patterns of linkage disequilibrium between an inversion and allozymic loci within it or nearby have been used in attempts to discriminate among different hypotheses for the maintenance of variability. The interpretation of the data on the best-documented case, that of the nonrandom association between In(2L)t and alpha-Gpdh or Adh in the second chromosome of Drosophila melanogaster, has been done on the basis that recombination between alpha-Gpdh and Adh is almost entirely due to the recombination between In(2L)t and the locus within it (alpha-Gpdh), the recombination between the inversion and the nearby locus (Adh) being negligible. In this paper, we show that the pattern of recombination is just the opposite.
倒位与其内部或附近的等位酶基因座之间连锁不平衡的发生情况和模式,已被用于尝试区分维持变异性的不同假说。对于记录最完备的案例,即黑腹果蝇第二染色体上In(2L)t与α-Gpdh或Adh之间的非随机关联的数据解释,是基于α-Gpdh和Adh之间的重组几乎完全归因于In(2L)t与其内部基因座(α-Gpdh)之间的重组,而倒位与附近基因座(Adh)之间的重组可忽略不计这一前提。在本文中,我们表明重组模式恰恰相反。