Department of Crop Protection, Zhejiang Agriculture and Forest University, Hangzhou 311300, China.
Department of Plant Pathology and Microbiology, and Institute for Plant Genomics and Biotechnology, Texas A&M University, College Station, TX 77843, U.S.A.
Phytopathology. 2019 Oct;109(10):1679-1688. doi: 10.1094/PHYTO-01-19-0012-R. Epub 2019 Sep 3.
Alternative oxidase (AOX) is a ubiquinol terminal oxidase that is involved in fungal mitochondrial oxidative phosphorylation. In this study, we analyzed the roles of AOX in by generating BcAOX deletion mutants. The mutants exhibited defects in mycelial growth, sporulation, spore germination, and virulence. Furthermore, the sensitivity of the mutants to quinone outside inhibitor fungicides and oxidative stress were increased. All phenotypic variations could be restored in the complemented strain. In summary, these results showed that BcAOX is involved in the regulation for vegetative development, adaptation to environmental stress, and virulence of .
交替氧化酶（AOX）是一种参与真菌线粒体氧化磷酸化的泛醌末端氧化酶。在这项研究中，我们通过生成 BcAOX 缺失突变体来分析 AOX 在 中的作用。突变体表现出菌丝生长、孢子形成、孢子萌发和毒力缺陷。此外，突变体对醌外抑制剂杀菌剂和氧化应激的敏感性增加。在互补菌株中可恢复所有表型变化。总之，这些结果表明 BcAOX 参与了 的营养生长发育、适应环境胁迫和毒力的调节。
