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用于微粒介电泳三维聚焦的喷嘴形电极配置

Nozzle-Shaped Electrode Configuration for Dielectrophoretic 3D-Focusing of Microparticles.

作者信息

Krishna Salini, Alnaimat Fadi, Mathew Bobby

机构信息

Mechanical Engineering Department, United Arab Emirates University, Al Ain 15551, UAE.

National Water Center, United Arab Emirates University, Al Ain, UAE.

出版信息

Micromachines (Basel). 2019 Aug 31;10(9):585. doi: 10.3390/mi10090585.

DOI:10.3390/mi10090585
PMID:31480490
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6780211/
Abstract

An experimentally validated mathematical model of a microfluidic device with nozzle-shaped electrode configuration for realizing dielectrophoresis based 3D-focusing is presented in the article. Two right-triangle shaped electrodes on the top and bottom surfaces make up the nozzle-shaped electrode configuration. The mathematical model consists of equations describing the motion of microparticles as well as profiles of electric potential, electric field, and fluid flow inside the microchannel. The influence of forces associated with inertia, gravity, drag, virtual mass, dielectrophoresis, and buoyancy are taken into account in the model. The performance of the microfluidic device is quantified in terms of horizontal and vertical focusing parameters. The influence of operating parameters, such as applied electric potential and volumetric flow rate, as well as geometric parameters, such as electrode dimensions and microchannel dimensions, are analyzed using the model. The performance of the microfluidic device enhances with an increase in applied electric potential and reduction in volumetric flow rate. Additionally, the performance of the microfluidic device improves with reduction in microchannel height and increase in microparticle radius while degrading with increase in reduction in electrode length and width. The model is of great benefit as it allows for generating working designs of the proposed microfluidic device with the desired performance metrics.

摘要

本文提出了一种经过实验验证的微流控装置数学模型,该装置具有喷嘴形电极配置,用于实现基于介电泳的三维聚焦。顶部和底部表面的两个直角三角形电极构成了喷嘴形电极配置。该数学模型由描述微颗粒运动以及微通道内电势、电场和流体流动轮廓的方程组成。模型中考虑了与惯性、重力、阻力、虚质量、介电泳和浮力相关的力的影响。微流控装置的性能通过水平和垂直聚焦参数进行量化。使用该模型分析了操作参数(如施加的电势和体积流量)以及几何参数(如电极尺寸和微通道尺寸)的影响。微流控装置的性能随着施加电势的增加和体积流量的降低而增强。此外,微流控装置的性能随着微通道高度的降低和微颗粒半径的增加而提高,而随着电极长度和宽度的减小而降低。该模型具有很大的益处,因为它允许生成具有所需性能指标的所提出的微流控装置的工作设计。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/e73cafebd143/micromachines-10-00585-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/bddd246fad4a/micromachines-10-00585-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/79336ceb55d1/micromachines-10-00585-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/bf1448b423f8/micromachines-10-00585-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/003a5a09c2ec/micromachines-10-00585-g004a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/6d7bd233aa1e/micromachines-10-00585-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/f19a310d4064/micromachines-10-00585-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/b4965d4f7ea6/micromachines-10-00585-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/79cc5ef86d92/micromachines-10-00585-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/a3cdb9f2d9d4/micromachines-10-00585-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/3026aadda4bb/micromachines-10-00585-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/e73cafebd143/micromachines-10-00585-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/bddd246fad4a/micromachines-10-00585-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/79336ceb55d1/micromachines-10-00585-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/bf1448b423f8/micromachines-10-00585-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/003a5a09c2ec/micromachines-10-00585-g004a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/6d7bd233aa1e/micromachines-10-00585-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/f19a310d4064/micromachines-10-00585-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/b4965d4f7ea6/micromachines-10-00585-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/79cc5ef86d92/micromachines-10-00585-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/a3cdb9f2d9d4/micromachines-10-00585-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/3026aadda4bb/micromachines-10-00585-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a1/6780211/e73cafebd143/micromachines-10-00585-g011.jpg

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