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结直肠手术再次手术的危险因素。

Risk factors in reoperations in colorectal surgery.

作者信息

Zawadzki Marek, Krzystek-Korpacka Małgorzata, Rząca Marek, Czarnecki Roman, Obuszko Zbigniew, Sitarska Magdalena, Witkiewicz Wojciech

机构信息

Oddział Chirurgii Onkologicznej, Wojewódzki Szpital Specjalistyczny we Wrocławiu.

Katedra i Zakład Biochemii Lekarskiej, Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu.

出版信息

Pol Przegl Chir. 2019 May 15;91(4):13-18. doi: 10.5604/01.3001.0013.1922.

Abstract

BACKGROUND

Reoperations in colorectal surgery are usually a consequence of major surgical complications. Recently, the rate of reoperation has been proposed as a marker of surgical performance. Yet, the incidence of re-intervention varies significantly in literature, ranging from 5.2% to 13%. Therefore, in this study we investigated 30-day reoperation rates and made an attempt to identify risk factors of re-intervention following colorectal resection at our institution.

METHODS

This is a retrospective study of patients who had undergone colorectal resection at a single institution from 2013 to 2017. Univariate and multivariate analysis of predicting factors were performed.

RESULTS

Out of 464 patients included, 51 required reoperations (11%). The most common causes of reoperations were anastomotic leakage, postoperative bleeding, and wound dehiscence. In univariate analysis the age of the patient and location of the tumor were related to an increased rate of reoperation. In multivariate analysis patients older than 75 (OR = 2.1; 95%CI = 1.1-3.9) and tumors sited in the rectum (OR = 2.66; 95%CI = 1.4-5) were associated with an increased risk of re-intervention. Patients who required postoperative re-intervention stayed in hospital longer (14 vs. 6 days, P < 0.0001) and had higher mortality (9.8% vs. 1.2%, P = 0.002).

CONCLUSIONS

Our study shows that reoperation rates that follow colorectal surgery are frequently undervalued. In our series, 11% of patients required an unplanned return to the operative room. Patient's age and rectal tumors were the two independent factors that affect the rate of reoperation. Novel aspect: Data concerning reoperation rates in colorectal surgery is varying and most reports have shown the incidence of re-intervention to be as low as 5-7%. Our study demonstrates that reoperations after curative surgery for colorectal cancer are more frequent and may occur in over a tenth of total patients operated on.

摘要

背景

结直肠手术再次手术通常是重大手术并发症的结果。最近,再次手术率已被提议作为手术表现的一个指标。然而,再次干预的发生率在文献中差异很大,从5.2%到13%不等。因此,在本研究中,我们调查了30天再次手术率,并试图确定我院结直肠切除术后再次干预的危险因素。

方法

这是一项对2013年至2017年在单一机构接受结直肠切除术患者的回顾性研究。对预测因素进行单因素和多因素分析。

结果

在纳入的464例患者中,51例需要再次手术(11%)。再次手术最常见的原因是吻合口漏、术后出血和伤口裂开。单因素分析中,患者年龄和肿瘤位置与再次手术率增加有关。多因素分析中,年龄大于75岁(OR = 2.1;95%CI = 1.1 - 3.9)和肿瘤位于直肠(OR = 2.66;95%CI = 1.4 - 5)与再次干预风险增加相关。需要术后再次干预的患者住院时间更长(14天对6天,P < 0.0001)且死亡率更高(9.8%对1.2%,P = 0.002)。

结论

我们的研究表明,结直肠手术后的再次手术率经常被低估。在我们的系列研究中,11%的患者需要意外返回手术室。患者年龄和直肠肿瘤是影响再次手术率的两个独立因素。新观点:关于结直肠手术再次手术率的数据各不相同,大多数报告显示再次干预的发生率低至5 - 7%。我们的研究表明,结直肠癌根治性手术后的再次手术更为频繁,可能发生在超过十分之一的手术患者中。

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