Ammendola Michele, Ruggiero Michele, Talarico Carlo, Memeo Riccardo, Ammerata Giorgio, Capomolla Antonella, Filippo Rosalinda, Romano Roberto, Pallio Socrate, Navarra Giuseppe, Montemurro Severino, Currò Giuseppe
Science of Health Department, Digestive Surgery Unit, "Mater Domini" Hospital, University "Magna Graecia" Medical School, Viale Europa, Germaneto, 88100, Catanzaro, Italy.
Hepato-Biliary and Pancreatic Surgical Unit, "F. Miulli" Hospital, Acquaviva delle Fonti, Bari, Italy.
World J Surg Oncol. 2020 Dec 10;18(1):327. doi: 10.1186/s12957-020-02096-z.
Colorectal cancer (CRC) is the most common tumor of the gastrointestinal tract. Anastomotic leak (AL) and prolonged postoperative ileus (PPOI) are two important complications of colorectal surgery. In this observational retrospective study, we evaluated the positive effects of transanal tube No Coil® in patients with CRC undergoing low anterior resection (LAR) and left hemicolectomy (LC).
Thirty-eight cases and forty controls resulted eligible for the final sample. No Coil® placement (SapiMed Spa, Alessandria, Italy) was considered an inclusion criteria for the case group. No Coil® was placed immediately after the end of surgical treatment.
PPOI was significantly more frequent in the control group. AL was evident in 1 patient (2.6%) of cases and 3 patients (7.5%) of controls. No statistical difference was found in AL occurrence between groups. POI days and AL resulted associated with hospital stay. POI days were negatively associated with No Coil placement and positively with AL.
With our preliminary data, we suggest that No Coil® placement can be considered as a valuable procedure assisting colorectal surgery, but further studies are required to confirm and enlarge actual evidence.
结直肠癌（CRC）是胃肠道最常见的肿瘤。吻合口漏（AL）和术后肠梗阻延长（PPOI）是结直肠手术的两个重要并发症。在这项观察性回顾性研究中，我们评估了经肛门放置No Coil®管对接受低位前切除术（LAR）和左半结肠切除术（LC）的CRC患者的积极作用。
最终样本包括38例病例和40例对照。病例组的纳入标准为放置No Coil®管（意大利亚历山德里亚的SapiMed Spa公司生产）。手术治疗结束后立即放置No Coil®管。
PPOI在对照组中明显更常见。病例组中有1例患者（2.6%）出现AL，对照组中有3例患者（7.5%）出现AL。两组之间AL的发生率无统计学差异。POI天数和AL与住院时间相关。POI天数与是否放置No Coil®管呈负相关，与AL呈正相关。
根据我们的初步数据，我们建议放置No Coil®管可被视为辅助结直肠手术的一种有价值的方法，但需要进一步研究来证实并扩大现有证据。
