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脂肪源性干细胞在增生性瘢痕治疗中的新进展。

New Progress of Adipose-derived Stem Cells in the Therapy of Hypertrophic Scars.

机构信息

Department of Burns and Cutaneous Surgery, Xijing Hospital, the Fourth Military Medical University, Xi' an, Shaanxi, China.

出版信息

Curr Stem Cell Res Ther. 2020;15(1):77-85. doi: 10.2174/1574888X14666190904125800.

Abstract

Burns are a global public health issue of great concern. The formation of scars after burns and physical dysfunction of patients remain major challenges in the treatment of scars. Regenerative medicine based on cell therapy has become a hot topic in this century. Adipose-derived stem cells (ADSCs) play an important role in cellular therapy and have become a promising source of regenerative medicine and wound repair transplantation. However, the anti-scarring mechanism of ADSCs is still unclear yet. With the widespread application of ADSCs in medical, we firmly believe that it will bring great benefits to patients with hypertrophic scars.

摘要

烧伤是一个全球性的公共卫生问题,备受关注。烧伤后形成的疤痕以及患者的身体功能障碍仍然是疤痕治疗的主要挑战。基于细胞治疗的再生医学已成为本世纪的热门话题。脂肪来源的干细胞(ADSCs)在细胞治疗中发挥着重要作用,已成为再生医学和创伤修复移植的有前途的来源。然而,ADSCs 的抗疤痕形成机制尚不清楚。随着 ADSCs 在医学中的广泛应用,我们坚信它将给增生性瘢痕患者带来巨大的益处。

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