Laboratory of Microbiology, Research Laboratory for Microorganisms and Human Disease, Habib Bourguiba University Hospital, University of Sfax, Sfax, Tunisia.
Burns unit, Habib Bourguiba University Hospital, Sfax, Tunisia.
J Med Microbiol. 2019 Oct;68(10):1540-1543. doi: 10.1099/jmm.0.001071. Epub 2019 Aug 22.
Four group A streptococcus (GAS) bacteraemia occurred in a small burn unit within 2 weeks. The GAS patient isolates, characterized as emm89, shared the same PFGE pulsotype with two other strains isolated 2 months later. The outbreak investigation revealed that a nurse was the most likely source of GAS transmission, as she was confirmed to carry the same outbreak strain in her throat and had direct and regular contact with the six outbreak patients in the unit. The outbreak was controlled after the nurse had undergone eradication treatment. This report highlights the emergence of the emm89 clone and its capacity to elicit invasive GAS outbreaks.
在两周内,一个小型烧伤病房中发生了四起 A 组链球菌(GAS)菌血症。GAS 患者分离株,特征为 emm89,与两个月后分离的另外两株具有相同的 PFGE 脉冲场凝胶电泳模式。暴发调查显示,一名护士是 GAS 传播的最可能来源,因为她的喉咙中携带相同的暴发株,并且与病房中的六名暴发患者有直接且规律的接触。在护士接受清除治疗后,暴发得到了控制。本报告强调了 emm89 克隆的出现及其引发侵袭性 GAS 暴发的能力。