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一例采用保守治疗的非典型胸锁关节化脓性关节炎。

An atypical sternoclavicular septic arthritis that was treated conservatively.

作者信息

Yeak R D K, Hussin P, Yap Y Y, Nizlan N M

出版信息

G Chir. 2019 May-Jun;40(3):243-247.

Abstract

Sternoclavicular joint infection is rare. While it is usually treated surgically, we wish to report a case of non-operative treatment of such infection caused by an atypical organism. A 51-year-old woman, known case of diabetes mellitus, hypertension, dyslipidaemia and hyperthyroidism presented with pain over the left upper chest for two weeks associated with redness and fever for one week. The patient was diagnosed to have left sternoclavicular joint septic arthritis with medial end left clavicular osteomyelitis, left sternocleidomastoid, left anterior chest wall abscesses and left lower lobe posterior basal segment cavitating lung lesion with a single nodule in the lingular segment. The blood culture and sensitivity grew extended spectrum beta lactamase (ESBL) Klebsiella pneumonia and the patient was treated with two weeks of meropenem. Computed Tomography was then repeated 2 months later and features were suggestive resolving of left sternoclavicular joint septic arthritis with medial end left clavicular osteomyelitis. The patient is still under surveillance and is currently symptom free 1 year later. We present a case to our knowledge is the first case of rare gram negative rod organism, ESBL Klebsiella pneumoniae infection which caused the left sternoclavicular septic arthritis with medial end left clavicular osteomyelitis, left sternocleidomastoid and left anterior chest wall abscesses. The patient is most likely immunocompromised from being a diabetic with hyperthyroidism. First line treatment can be with antibiotics and when that fails, patient can be treated surgically. Two weeks of antibiotics therapy is possible in selected patients with monitoring of the infective markers.

摘要

胸锁关节感染较为罕见。虽然通常采用手术治疗,但我们希望报告一例由非典型病原体引起的此类感染的非手术治疗病例。一名51岁女性,已知患有糖尿病、高血压、血脂异常和甲状腺功能亢进,出现左上胸部疼痛两周,伴有发红和发热一周。患者被诊断为左胸锁关节化脓性关节炎伴左锁骨内侧端骨髓炎、左胸锁乳突肌、左前胸壁脓肿以及左下叶后基底段空洞性肺病变,舌叶段有单个结节。血培养及药敏结果显示产超广谱β-内酰胺酶(ESBL)的肺炎克雷伯菌,患者接受了两周的美罗培南治疗。两个月后重复进行计算机断层扫描,结果提示左胸锁关节化脓性关节炎伴左锁骨内侧端骨髓炎有所好转。患者仍在接受监测,1年后目前无症状。据我们所知,我们报告的这例病例是首例由罕见的革兰氏阴性杆菌病原体——产ESBL肺炎克雷伯菌感染引起的左胸锁关节化脓性关节炎伴左锁骨内侧端骨髓炎、左胸锁乳突肌和左前胸壁脓肿。该患者很可能因患有糖尿病和甲状腺功能亢进而免疫功能低下。一线治疗可使用抗生素,若治疗失败,患者可接受手术治疗。对于部分患者,在监测感染指标的情况下,进行两周的抗生素治疗是可行的。

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