Raděj Jaroslav, Horák Jan, Harazim Martin, Matějovič Martin
Vnitr Lek. 2019 Summer;65(6):425-432.
The second part of the review deals in detail with the diagnostics and treatment of toxic alcohols poisoning and management and indication of extracorporeal removal techniques in intoxication with other drugs, theophylline, valproic acid, metformin and metformin associated lactic acidosis, respectively. The extracorporeal treatment enhances the clearance of the toxin and corrects patients metabolic disturbances as well. It is necessary to use this treatment in severe intoxications. Indication of this invasive procedure falls within clinicians and nephrologists competence being advised by a toxicologist. This review could help make fast decisions.
综述的第二部分详细论述了有毒醇类中毒的诊断与治疗，以及分别针对其他药物、茶碱、丙戊酸、二甲双胍和二甲双胍相关乳酸酸中毒中毒时体外清除技术的管理与适应证。体外治疗可提高毒素清除率，同时纠正患者的代谢紊乱。在严重中毒时必须采用这种治疗方法。这种侵入性操作的适应证由毒理学家提供建议，属于临床医生和肾病学家的职责范围。本综述有助于做出快速决策。
