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经皮肾镜取石术评分系统的应用有多实用?比较盖伊结石评分、S.T.O.N.E.评分和腔内泌尿外科临床研究办公室(CROES)列线图的前瞻性研究。

How practical is the application of percutaneous nephrolithotomy scoring systems? Prospective study comparing Guy's Stone Score, S.T.O.N.E. score and the Clinical Research Office of the Endourological Society (CROES) nomogram.

作者信息

Singla Anurag, Khattar Nikhil, Nayyar Rishi, Mehra Shibani, Goel Hemant, Sood Rajeev

机构信息

Department of Urology, Postgraduate Institute of Medical Education and Research (PGIMER) and Dr. Ram Manohar Lohia Hospital, Baba Kharak Singh Marg, New Delhi, Delhi, India.

Department of Radio-diagnosis, Postgraduate Institute of Medical Education and Research (PGIMER) and Dr. Ram Manohar Lohia Hospital, Baba Kharak Singh Marg, New Delhi, Delhi, India.

出版信息

Arab J Urol. 2017 Jan 12;15(1):7-16. doi: 10.1016/j.aju.2016.11.005. eCollection 2017 Mar.

Abstract

OBJECTIVE

To prospectively compare the Guy's Stone Score (GSS), S.T.O.N.E. [stone size (S), tract length (T), obstruction (O), number of involved calices (N), and essence or stone density (E)] score and the Clinical Research Office of the Endourological Society (CROES) nephrolithometric nomogram to predict percutaneous nephrolithotomy (PCNL) success rate and assess the correlation with perioperative complications.

PATIENTS AND METHODS

We prospectively evaluated all consecutive PCNL patients at our institute between 1 November 2013 and 31 May 2015. The above scoring systems were applied to preoperative non-contrast computed tomography and the practical difficulties in such applications were noted. Perioperative complications and the stone-free rate (SFR) were also recorded. Receiver operating characteristic curves were drawn and the areas under curves were compared and appropriate statistical analysis done.

RESULTS

In all, 48 renal units were included in the study. The overall SFR was 62.2%. The presence of staghorn stones ( = 27.285, 95% confidence interval 1.19-625.35;  = 0.039) was the only significant variable associated with the residual stones on multivariate analysis. Stone-free patients had significantly lower median GSS (2 vs 4) and S.T.O.N.E. scores (6 vs 10) and higher median CROES scores (83% vs 63%) (all  < 0.001) compared to residual-stone patients. All scoring systems were significantly associated with SFR (all  < 0.001). There was no significant difference in the areas under curves of the scoring systems (0.858, 0.923, and 0.931, respectively). Furthermore, all scoring systems had weak correlations with Clavien-Dindo classified complications ( = 0.29,  = 0.045;  = 0.40,  = 0.005 and  = -0.295,  = 0.04, respectively). We found no standardisation for the measurement of stone dimensions, tract length, Hounsfield units, and staghorn definition.

CONCLUSIONS

All scoring systems equally predicted SFR and had a weak correlation with Clavien-Dindo complications. Standardisation is needed for the variables in which they have been found deficient.

摘要

目的

前瞻性比较盖伊结石评分(GSS)、S.T.O.N.E. [结石大小(S)、通道长度(T)、梗阻(O)、受累肾盏数量(N)以及结石本质或密度(E)]评分和腔内泌尿外科协会临床研究办公室(CROES)肾结石测量列线图,以预测经皮肾镜取石术(PCNL)成功率,并评估与围手术期并发症的相关性。

患者与方法

我们前瞻性评估了2013年11月1日至2015年5月31日期间在我院接受连续PCNL治疗的所有患者。将上述评分系统应用于术前非增强计算机断层扫描,并记录应用过程中的实际困难。同时记录围手术期并发症和结石清除率(SFR)。绘制受试者工作特征曲线,比较曲线下面积并进行适当的统计分析。

结果

本研究共纳入48个肾单位。总体SFR为62.2%。鹿角形结石的存在(=27.285,95%置信区间1.19 - 625.35;=0.039)是多因素分析中与残留结石相关的唯一显著变量。与有残留结石的患者相比,结石清除的患者GSS中位数(2比4)和S.T.O.N.E.评分(6比10)显著更低,CROES评分中位数更高(83%比63%)(均<0.001)。所有评分系统均与SFR显著相关(均<0.001)。各评分系统曲线下面积无显著差异(分别为0.858、0.923和0.931)。此外,所有评分系统与Clavien - Dindo分类并发症的相关性均较弱(分别为=0.29,=0.045;=0.40,=0.005和=-0.295,=0.04)。我们发现结石尺寸、通道长度、亨氏单位和鹿角形定义的测量没有标准化。

结论

所有评分系统对SFR的预测效果相同,且与Clavien - Dindo并发症的相关性较弱。对于已发现存在缺陷的变量,需要进行标准化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bacf/5329720/abaacdabd668/gr1.jpg

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