Markus Hugh
Stroke Research Group, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK
Pract Neurol. 2020 Feb;20(1):34-38. doi: 10.1136/practneurol-2018-002006. Epub 2019 Sep 4.
Stroke is a syndrome caused by many different disease mechanisms rather than being a single disease. It is important to identify the underlying mechanism accurately in individual patients in order to choose the best treatment approach. This article provides practical tips to diagnose the underlying subtype of stroke, and in particular discusses non-lacunar pathologies that can present with a clinical lacunar syndrome. It also reviews the recent advances in recurrent stroke prevention, including using more intensive antiplatelet regimens in the acute phase, and the concept that undetected cardiac arrhythmias may be important in apparently cryptogenic stroke.
中风是由多种不同疾病机制引起的综合征，而非单一疾病。准确识别个体患者的潜在机制对于选择最佳治疗方法至关重要。本文提供了诊断中风潜在亚型的实用技巧，尤其讨论了可表现为临床腔隙综合征的非腔隙性病变。文章还综述了复发性中风预防方面的最新进展，包括在急性期使用更强化的抗血小板方案，以及未被检测到的心律失常可能在明显原因不明的中风中起重要作用这一概念。
