Keyal Niraj Kumar, Thapa Sumal, Yadav Manoj Kumar
Department of Critical Care and Emergency Medicine, B&C Medical College Teaching Hospital and Research Centre, Jhapa, Nepal.
Department of Anesthesia and Critical Care, B&C Medical College Teaching Hospital and Research Centre, Jhapa, Nepal.
Indian J Crit Care Med. 2019 Aug;23(8):380-381. doi: 10.5005/jp-journals-10071-23224.
Carbimazole is an antithyroid drug that rarely presents as anaphylactic shock. We hereby report a case of 40-year-old female who was treated with carbimazole for thyrotoxicosis. Patient developed sweating, shortness of breath and altered sensorium after taking single dose of carbimazole. Patient was treated for anaphylactic shock. From this, we want to emphasize that carbimazole can rarely present as anaphylactic shock without any other allergic manifestation. So, patient should be counselled about this rare side effect and early approach to health care facility.
Patient on carbimazole should be aware of all side effects including rare side effects like anaphylactic shock. Studies are required to identify risk factors and new drugs for carbimazole allergy patients. Patient with thyrotoxicosis should also be screened for autoimmune thyrotoxicosis.
Keyal NK, Thapa S, Yadav MK. Carbimazole-induced Anaphylactic Shock: A Case Report. Indian J Crit Care Med 2019;23(8):380-381.
卡比马唑是一种抗甲状腺药物,很少引起过敏性休克。我们在此报告一例40岁女性,因甲状腺毒症接受卡比马唑治疗。患者在服用单剂量卡比马唑后出现出汗、呼吸急促和意识改变。患者接受了过敏性休克治疗。由此,我们想强调卡比马唑很少会在没有任何其他过敏表现的情况下引起过敏性休克。因此,应向患者告知这种罕见的副作用以及出现症状后应尽早前往医疗机构就诊。
服用卡比马唑的患者应了解所有副作用,包括过敏性休克等罕见副作用。需要开展研究以确定卡比马唑过敏患者的风险因素和新药。甲状腺毒症患者也应筛查自身免疫性甲状腺毒症。
Keyal NK, Thapa S, Yadav MK. 卡比马唑诱发的过敏性休克:一例报告。《印度重症监护医学杂志》2019年;23(8):380 - 381。