Department of Persian Medicine, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Obstetrics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Phytother Res. 2020 Jan;34(1):118-125. doi: 10.1002/ptr.6502. Epub 2019 Sep 4.
Given the importance of heavy menstrual bleeding (HMB), we investigated the effect of plantain syrup on HMB. This randomized clinical trial was performed on 68 women with HMB who were referred to the traditional medicine clinics of Mashhad University of Medical Sciences. The intervention group received placebo capsule and plantain syrup, whereas the control group received mefenamic acid capsule and placebo syrup in the first 5 days of menstruation for three menstruation cycles. Patients were asked to complete pictorial blood assessment chart one cycle before the intervention and three intervention cycles. Hemoglobin was measured at the beginning and at the end of the study. The results showed that the bleeding duration and severity diminished in both groups. No significant difference was observed between two groups in severity of bleeding after intervention (Cohen's d = .24), but duration of bleeding in mefenamic acid group was reduced significantly in comparison with plantain group (Cohen's d = .57). Although mean hemoglobin alterations in mefenamic acid group had a significant difference before and after the intervention, there was no significant difference between the two groups in mean hemoglobin alterations postintervention. Plantain syrup could be suggested as a complementary treatment for HMB, but further studies are required.
鉴于月经过多（HMB）的重要性，我们研究了车前草糖浆对 HMB 的影响。这项随机临床试验在马什哈德医科大学传统医学诊所招募了 68 名 HMB 患者。干预组服用安慰剂胶囊和车前草糖浆，而对照组在月经的前 5 天服用甲芬那酸胶囊和安慰剂糖浆，持续三个月经周期。患者在干预前一个周期和三个干预周期内完成了图像血液评估图表。在研究开始和结束时测量血红蛋白。结果表明，两组的出血持续时间和严重程度均有所减轻。干预后两组出血严重程度无显著差异（Cohen's d =.24），但甲芬那酸组的出血持续时间与车前草组相比显著减少（Cohen's d =.57）。虽然甲芬那酸组的平均血红蛋白变化在干预前后有显著差异，但干预后两组之间的平均血红蛋白变化无显著差异。车前草糖浆可以作为 HMB 的辅助治疗方法，但需要进一步的研究。
