Section of Radiological Sciences, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Palermo, Italy.
IRCCS Istituto Ortopedico Galeazzi, Unit of Diagnostic and Interventional Radiology, Milan, Italy.
Hematol Oncol. 2020 Feb;38(1):12-21. doi: 10.1002/hon.2676. Epub 2019 Nov 13.
The improvements in magnetic resonance imaging (MRI) technology and the concern related to the increased cancer risk in patients with lymphoma, also due to radiation exposure associated with imaging examinations, have led to the introduction of whole-body MRI (WB-MRI) as a radiation-free alternative to standard imaging procedures. WB-MRI seems a less histology-dependent functional imaging test than F-fluorodeoxyglucose-positron emission tomography/CT ( F-FDG-PET/CT). In patients with FDG-avid lymphomas, such as diffuse large B-cell lymphoma (DLBCL) and Hodgkin lymphoma (HL), F-FDG-PET/CT remains the imaging reference standard for staging, with WB-MRI potentially being a complementary modality that could replace CT, especially in young patients. On the other hand, WB-MRI is a valuable imaging procedure for lymphoma surveillance and in lymphomas with variable/low FDG avidity and nonfollicular indolent lymphomas. The aim of this paper is to discuss the current state of the art of WB-MRI in lymphoma by evaluating its diagnostic performance in different lymphoma subtypes: Hodgkin, aggressive, and indolent lymphomas.
磁共振成像（MRI）技术的改进，以及淋巴瘤患者因辐射暴露与影像学检查相关的癌症风险增加的担忧，促使人们引入全身 MRI（WB-MRI）作为一种无辐射的标准影像学检查替代方法。WB-MRI 似乎是一种比 F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（ F-FDG-PET/CT）更依赖于组织学的功能性成像检测。在 FDG 摄取的淋巴瘤患者中，如弥漫性大 B 细胞淋巴瘤（DLBCL）和霍奇金淋巴瘤（HL）， F-FDG-PET/CT 仍然是分期的影像学参考标准，而 WB-MRI 可能是一种补充方式，可以替代 CT，特别是在年轻患者中。另一方面，WB-MRI 是淋巴瘤监测和具有可变/低 FDG 摄取率和非滤泡性惰性淋巴瘤的有价值的影像学检查方法。本文旨在通过评估 WB-MRI 在不同淋巴瘤亚型中的诊断性能，来讨论其在淋巴瘤中的最新技术状况：霍奇金淋巴瘤、侵袭性淋巴瘤和惰性淋巴瘤。
