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全面面部治疗采用肉毒毒素 A:来自单中心研究的结果。

Full-face treatment with onabotulinumtoxinA: Results from a single-center study.

机构信息

Villa Salaria, Rome, Italy.

出版信息

J Cosmet Dermatol. 2020 Apr;19(4):809-816. doi: 10.1111/jocd.13130. Epub 2019 Sep 5.

Abstract

BACKGROUND

Botulinum toxin type A injection is a common aesthetic treatment that can be used alone or in combination to rejuvenate the entire face and neck.

OBJECTIVES

To assess the safety and efficacy of a full-face approach with botulinum toxin type A.

METHODS

This was a single-center, retrospective review of data from 189 patients receiving full-face and neck treatment with onabotulinumtoxinA in the following areas: glabellar lines, crow's feet lines, forehead lines, bunny lines, sagging nasal tip, gummy smile, marionette lines, mentalis, masseter, and lateral/anterior platysma.

RESULTS

The mean age was 56.6 ± 9.2 years, and 94.7% were women (n = 179). Patients received a total of 394 full-face treatments (mean: 2.1 per person; range 1-7). The mean quantity of onabotulinumtoxinA injected was 113.8 ± 17.6 units per treatment (range: 50-180 units). The most frequently injected areas were the glabella/crow's feet/forehead (n = 383; 97.2%), platysma (n = 378; 95.9%), bunny lines (n = 283; 71.8%), and chin (n = 120; 30.5%). Six patients (3.2%) experienced complications: five cases of unwanted diffusion from the mentalis into the depressor labii inferioris and one case of right eyelid ptosis after injection in the upper third. All were minor and none appeared to be related to overall dose.

CONCLUSIONS

Full-face and neck treatment with onabotulinumtoxinA can be performed without substantial safety concerns, often leading to excellent results. This approach may become increasingly prevalent in the coming years.

摘要

背景

肉毒毒素 A 注射是一种常见的美容治疗方法,可单独使用或联合使用,以恢复整个面部和颈部的年轻状态。

目的

评估肉毒毒素 A 全面部治疗的安全性和疗效。

方法

这是一项单中心、回顾性研究,共纳入 189 例接受肉毒毒素 A 全面部和颈部治疗的患者,治疗区域包括:眉间纹、鱼尾纹、额纹、鼻唇沟、鼻尖下垂、露龈笑、木偶纹、颏肌、咬肌和侧/前颈阔肌。

结果

患者的平均年龄为 56.6±9.2 岁,94.7%为女性(n=179)。患者共接受 394 次全面部治疗(平均每人 2.1 次;范围 1-7 次)。每次治疗肉毒毒素 A 的平均用量为 113.8±17.6 单位(范围:50-180 单位)。最常注射的区域是眉间/鱼尾纹/额部(n=383;97.2%)、颈阔肌(n=378;95.9%)、鼻唇沟(n=283;71.8%)和颏部(n=120;30.5%)。6 例(3.2%)患者出现并发症:5 例因颏肌注射导致肉毒毒素向降口角肌扩散,1 例上三分之一注射后出现右侧眼睑下垂。所有并发症均为轻度,且似乎与总剂量无关。

结论

肉毒毒素 A 全面部和颈部治疗安全性较高,通常可获得良好的效果。这种治疗方法在未来几年可能会越来越普遍。

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