Department of Public Health Sciences, Stockholm University, Stockholm, Sweden.
Department of Clinical Neuroscience, Karolinska Institute, Solna, Sweden.
Acta Psychiatr Scand. 2019 Dec;140(6):563-573. doi: 10.1111/acps.13098. Epub 2019 Sep 21.
To examine the association between various indicators of father's alcohol use and suicidal behaviour in offspring during youth and young adulthood.
The study is based on a cohort of 68 910 Swedish citizens who were born between 1970 and 1985 and have fathers who participated in conscription for compulsory military training in 1969/70. Information on fathers' alcohol use was collected during conscription. Offspring was followed for suicide attempts or completed suicides (through linkage with national registers) from age 12 to end of follow-up in 2008.
After adjustment for confounders, the hazard ratio (HR) for offspring to fathers who were heavy drinkers was 1.4 (95% CI 1.02, 1.93) while the associations turned non-significant for offspring to fathers who often drank into intoxication, HR 1.14 (0.68, 1.90). The highest risk for suicidal behaviour was found for offspring to fathers who had been apprehended for drunkenness two times or more, or with an alcohol-related hospitalization, with adjusted HRs of 2.1 (1.4, 3,14) and 1.9 (1.27, 2,85) respectively.
Fathers' alcohol use is associated with increased risk of suicidal behaviour among offspring in youth and young adulthood.
探讨父亲饮酒的各种指标与青年和成年早期子女自杀行为之间的关联。
该研究基于一个队列，其中包括 1970 年至 1985 年间出生的 68910 名瑞典公民，他们的父亲曾在 1969/70 年参加过义务兵役的征兵。在征兵期间收集了关于父亲饮酒的信息。从 12 岁开始，通过与国家登记处的链接，对子女的自杀未遂或自杀死亡（通过与国家登记处的链接）进行随访，直到 2008 年随访结束。
调整混杂因素后，父亲为重度饮酒者的子女发生自杀企图的风险比（HR）为 1.4（95%CI 1.02,1.93），而父亲经常饮酒至醉酒的子女的相关性变得无统计学意义，HR 为 1.14（0.68,1.90）。对于因醉酒被捕两次或以上或因酒精相关住院治疗的父亲的子女，自杀行为的风险最高，调整后的 HR 分别为 2.1（1.4,3.14）和 1.9（1.27,2.85）。
父亲的饮酒与青年和成年早期子女自杀行为的风险增加有关。
