Durlach Martín, Echavarría Gonzalo, Antonucci Ricardo, Arias Tamara, Pensa Lucila, Fadel Daniel
área de Clínica Médica, Instituto de Investigaciones Médicas Alfredo Lanari, Universidad de Buenos Aires, Argentina. E-mail:
área de Clínica Médica, Instituto de Investigaciones Médicas Alfredo Lanari, Universidad de Buenos Aires, Argentina.
Medicina (B Aires). 2019;79(4):284-286.
Endomyocardial fibrosis is a restrictive cardiomyopathy with high morbidity and mortality rates, prevalent in the sub-Saharan Africa region but infrequent in our population. It has a close relation with blood hypereosinophilia. Hypoxic hepatitis is frequently observed in intensive care units and its diagnosis is clinical. It shows a typical enzyme pattern with high mortality too. There are multiple mechanisms responsible for this condition, such as ischemia, passive congestion and dysoxia. We described the case of a 35 year-old cocaine addict woman diagnosed with endomyocardial fibrosis and hypereosinophilic syndrome who developed cardiogenic shock with hypoxic hepatitis. The patient evolved favorably with the appropriate treatment.
心内膜心肌纤维化是一种发病率和死亡率较高的限制性心肌病，在撒哈拉以南非洲地区较为常见，但在我国人群中并不常见。它与血液嗜酸性粒细胞增多密切相关。缺氧性肝炎在重症监护病房中经常可见，其诊断主要依靠临床症状。它也呈现出典型的酶学模式，死亡率也很高。导致这种情况的机制有多种，如缺血、被动性充血和低氧血症。我们描述了一名35岁的可卡因成瘾女性病例，该患者被诊断为心内膜心肌纤维化和嗜酸性粒细胞增多综合征，并发展为心源性休克合并缺氧性肝炎。经过适当治疗，患者病情好转。
