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开放性腕管松解术与糖尿病:一项使用患者报告结局测量信息(PROMs)和国家质量登记处数据的回顾性研究

Open carpal tunnel release and diabetes: a retrospective study using PROMs and national quality registries.

作者信息

Zimmerman Malin, Eeg-Olofsson Katarina, Svensson Ann-Marie, Åström Mikael, Arner Marianne, Dahlin Lars

机构信息

Department of Translational Medicine - Hand Surgery, Lund University, Lund, Sweden

Department of Hand Surgery, Skånes universitetssjukhus Malmö, Malmo, Sweden.

出版信息

BMJ Open. 2019 Sep 4;9(9):e030179. doi: 10.1136/bmjopen-2019-030179.

DOI:10.1136/bmjopen-2019-030179
PMID:31488486
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6731852/
Abstract

OBJECTIVES

To study patient-reported outcome after open carpal tunnel release (OCTR) for carpal tunnel syndrome (CTS) in patients with or without diabetes using national healthcare quality registries.

DESIGN

Retrospective cohort study.

SETTING

Data from the Swedish National Quality Registry for Hand Surgery (HAKIR; www.hakir.se) were linked to data from the Swedish National Diabetes Register (NDR; www.ndr.nu).

PARTICIPANTS

We identified 9049 patients (10 770 hands) operated for CTS during the inclusion period (2010-2016).

PRIMARY OUTCOME MEASURES

Patient-reported outcome measures were analysed before surgery and at 3 and 12 months postoperatively using the QuickDASH as well as the HAKIR questionnaire with eight questions on hand symptoms and disability.

RESULTS

Patients with diabetes (n=1508; 14%) scored higher in the QuickDASH both preoperatively and postoperatively than patients without diabetes, but the total score change between preoperative and postoperative QuickDASH was equal between patients with and without diabetes. The results did not differ between patients with type 1 or type 2 diabetes. Patients with diabetic retinopathy scored higher in QuickDASH at 3 months postoperatively than patients with diabetes without retinopathy. In the regression analysis, diabetes was associated with more residual symptoms at 3 and 12 months postoperatively.

CONCLUSIONS

Patients with diabetes experience more symptoms both before and after OCTR, but can expect the same relative improvement from surgery as patients without diabetes . Patients with retinopathy, as a proxy for neuropathy, may need longer time for symptoms to resolve after OCTR. Smoking, older age, higher HbA1c levels and receiving a diabetes diagnosis after surgery were associated with more residual symptoms following OCTR.

摘要

目的

利用国家医疗质量登记系统,研究糖尿病患者和非糖尿病患者在接受开放性腕管松解术(OCTR)治疗腕管综合征(CTS)后的患者报告结局。

设计

回顾性队列研究。

设置

瑞典国家手部手术质量登记系统(HAKIR;www.hakir.se)的数据与瑞典国家糖尿病登记系统(NDR;www.ndr.nu)的数据相链接。

参与者

我们确定了9049例在纳入期(2010 - 2016年)接受CTS手术的患者(10770只手)。

主要结局指标

术前以及术后3个月和12个月,使用QuickDASH以及HAKIR关于手部症状和残疾的八个问题的问卷,分析患者报告的结局指标。

结果

糖尿病患者(n = 1508;14%)术前和术后的QuickDASH评分均高于非糖尿病患者,但术前和术后QuickDASH的总分变化在糖尿病患者和非糖尿病患者之间是相同的。1型或2型糖尿病患者的结果没有差异。糖尿病视网膜病变患者术后3个月的QuickDASH评分高于无视网膜病变的糖尿病患者。在回归分析中,糖尿病与术后3个月和12个月更多的残留症状相关。

结论

糖尿病患者在OCTR前后经历更多症状,但手术带来的相对改善与非糖尿病患者相同。视网膜病变患者作为神经病变的代表,OCTR后症状缓解可能需要更长时间。吸烟、年龄较大、HbA1c水平较高以及术后接受糖尿病诊断与OCTR后更多的残留症状相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b7/6731852/5b33d01164fe/bmjopen-2019-030179f04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b7/6731852/14a439b7c88b/bmjopen-2019-030179f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b7/6731852/8865c3fa35e9/bmjopen-2019-030179f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b7/6731852/e1252e8186a3/bmjopen-2019-030179f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b7/6731852/5b33d01164fe/bmjopen-2019-030179f04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b7/6731852/14a439b7c88b/bmjopen-2019-030179f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b7/6731852/8865c3fa35e9/bmjopen-2019-030179f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b7/6731852/e1252e8186a3/bmjopen-2019-030179f03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6b7/6731852/5b33d01164fe/bmjopen-2019-030179f04.jpg

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