未达到 5 分钟目标 SpO 饱和度的婴儿复苏结局。
Resuscitation outcomes of infants that do not achieve a 5 min target SpO saturation.
机构信息
Neonatal Research Institute at Sharp Mary Birch Hospital for Women and Newborns, San Diego, CA, USA.
出版信息
J Perinatol. 2019 Dec;39(12):1635-1639. doi: 10.1038/s41372-019-0491-x. Epub 2019 Sep 5.
OBJECTIVE
To determine differences in the duration and level of resuscitation between infants that achieve a peripheral oxygen saturation (SpO) of 80% by 5 min compared with those who remain below 80% saturation.
STUDY DESIGN
Infants < 32 weeks GA were analyzed. Pulse rate, SpO, airway pressure, and fraction of inspired oxygen were collected during the first 10 min of life.
RESULTS
Two hundred and eighty-four infants were analyzed of which 100 had SpO < 80% at 5 min of life. Composite outcome of death and any IVH was greater in the <80% at 5 min group. These infants had lower heart rates and lower SpO despite increased mean airway pressure and higher FiO (p < 0.001).
CONCLUSION
Infants <32 weeks GA that do not achieve a peripheral arterial saturation of 80% by 5 min of life experience more death or severe IVH. This association is amongst the strongest seen of any predictor of morbidity in the delivery room.
目的
确定在 5 分钟时外周血氧饱和度（SpO）达到 80%的婴儿与仍低于 80%饱和度的婴儿之间复苏持续时间和程度的差异。
研究设计
分析了胎龄 <32 周的婴儿。在生命的前 10 分钟收集了心率、SpO、气道压力和吸入氧分数。
结果
对 284 名婴儿进行了分析，其中 100 名婴儿在 5 分钟时 SpO<80%。在 5 分钟时<80%的组中，死亡和任何 IVH 的复合结局更大。尽管平均气道压力升高和 FiO 更高（p<0.001），但这些婴儿的心率较低，SpO 较低。
结论
胎龄 <32 周的婴儿在生命的 5 分钟时未达到外周动脉血氧饱和度 80%，经历更多的死亡或严重 IVH。这种关联是在分娩室中任何发病率预测因素中最强的之一。
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