Qureshi Sarah Shoaib, Amer Wasim, Kaleem Maryam, Beg Bilal Mahmood
Dr. Sarah Shoaib Qureshi, FCPS. Department of Medicine, Lahore Medical and Dental College Lahore, Pakistan.
Prof. Dr. Wasim Amer, FCPS. Department of Medicine, Lahore Medical and Dental College Lahore, Pakistan.
Pak J Med Sci. 2019 Sep-Oct;35(5):1284-1289. doi: 10.12669/pjms.35.5.759.
This study was aimed to compare the body mass index (BMI) and waist-to-hip ratio (WHR) in their ability to predict type 2 diabetes risk in a large prospective cohort of men and women in Pakistan.
This was a case-control study conducted at Diabetic and medical OPD of GTTH. Anthropometric measures including BMI and WHR were analyzed. Student's t-test, Chi-squared test along with Cramer's V value, was applied to evaluate association between variables. Receiver operating curve (ROC) was used to assess anthropometric measures.
The study included 804 diabetics and 396 non-diabetics between 30-60 years of age. Comparing the BMI parameters it was found that 717 (89.2%) in diabetic group were overweight or obese (p-value < 0.001). On comparing the WHR, 97.9% diabetics had increased WHR (p-value <0.001). Both BMI & WHR were further compared using ROC curve which found out that WHR had an area under ROC of 0.720 & BMI has 0.680, suggesting that WHR is more better predictor of diabetes as compared to BMI.
Both BMI and WHR were strong discriminators of T2DM but WHR was found superior according to ROC value. Family history is significantly associated in patients with diabetes.
本研究旨在比较体重指数(BMI)和腰臀比(WHR)在预测巴基斯坦一大群男性和女性2型糖尿病风险方面的能力。
这是一项在GTTH糖尿病和内科门诊进行的病例对照研究。分析了包括BMI和WHR在内的人体测量指标。应用学生t检验、卡方检验以及克莱默V值来评估变量之间的关联。采用受试者工作特征曲线(ROC)来评估人体测量指标。
该研究纳入了804名年龄在30至60岁之间的糖尿病患者和396名非糖尿病患者。比较BMI参数发现,糖尿病组中有717人(89.2%)超重或肥胖(p值<0.001)。比较WHR时,97.9%的糖尿病患者WHR升高(p值<0.001)。使用ROC曲线进一步比较BMI和WHR,发现WHR的ROC曲线下面积为0.720,BMI为0.680,这表明与BMI相比,WHR是更好的糖尿病预测指标。
BMI和WHR都是2型糖尿病的有力鉴别指标,但根据ROC值,WHR更具优势。家族史与糖尿病患者显著相关。