韩国人群腹部癌症手术后静脉血栓栓塞症：发生率和风险评估模型的验证。
Venous Thromboembolism Following Abdominal Cancer Surgery in the Korean Population: Incidence and Validation of a Risk Assessment Model.
机构信息
Division of Vascular and Transplant Surgery, Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Division of Vascular and Transplant Surgery, Department of Surgery, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu-si, Gyeonggi-do, Korea.
出版信息
Ann Surg Oncol. 2019 Nov;26(12):4037-4044. doi: 10.1245/s10434-019-07633-z. Epub 2019 Sep 5.
BACKGROUND
A cancer patient slated for abdominal surgery is considered to be at moderate to high risk for developing venous thromboembolism (VTE), but the incidence is quite low in Korean patients. Most risk assessment models and recommendations for VTE management are from Western reports, however they possibly overestimate the risk of VTE in the Korean population.
METHODS
We retrospectively reviewed the medical records of 1966 patients who were diagnosed with abdominal organ cancer and required surgical treatment.
RESULTS
Each patient was rated using the Caprini risk scoring model. The mean score was 7.5 ± 0.7 points; 98.4% of patients were classified as high risk for VTE. Symptomatic VTE occurred in eight patients, and the overall incidence was 0.4%. The mean Caprini score for VTE patients was 8.8 ± 1.9 points. In the group with scores between 5 and 9 points, the incidence was 0.3-0.5%, while in patients with scores > 10 points, the incidence of VTE was found to be 1.12%.
CONCLUSIONS
The risk stratification system in the Caprini scoring model needs to be modified based on the actual incidence in the Korean population.
背景
接受腹部手术的癌症患者被认为存在中度至高度发生静脉血栓栓塞症（VTE）的风险，但韩国患者的发病率相当低。大多数风险评估模型和 VTE 管理建议均来自西方报告，但它们可能高估了韩国人群的 VTE 风险。
方法
我们回顾性分析了 1966 例诊断为腹部器官癌症且需要手术治疗的患者的病历。
结果
每位患者均采用 Caprini 风险评分模型进行评分。平均得分为 7.5±0.7 分；98.4%的患者被归类为 VTE 高风险。8 例患者出现症状性 VTE，总发生率为 0.4%。VTE 患者的平均 Caprini 评分为 8.8±1.9 分。评分在 5 至 9 分的患者中，发生率为 0.3%-0.5%，而评分>10 分的患者 VTE 发生率为 1.12%。
结论
需要根据韩国人群的实际发生率对 Caprini 评分模型中的风险分层系统进行修正。
Zotero 插件