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先天性心脏病成人患者心脏手术前的冠状动脉疾病筛查

Coronary artery disease screening in adults with congenital heart disease prior to cardiac surgery.

作者信息

Johnson Bradley, Buelow Matthew, Earing Michael, Cohen Scott, Bartz Peter, Ginde Salil

机构信息

Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.

Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin.

出版信息

Congenit Heart Dis. 2019 Nov;14(6):895-900. doi: 10.1111/chd.12839. Epub 2019 Sep 6.

DOI:10.1111/chd.12839
PMID:31489771
Abstract

OBJECTIVE

As adults with congenital heart disease (CHD) grow older, preoperative screening for coronary artery disease (CAD) may be indicated prior to CHD surgery. Data regarding the indications for preoperative CAD screening in this population are limited. Current practice is to follow guidelines for patients with valvular heart disease; however, the risk for CAD in certain congenital heart diagnoses may be higher than the general population. This study aimed to assess the results of preoperative CAD screening in patients prior to CHD surgery.

DESIGN

Retrospective study.

SETTING

Single tertiary center.

PATIENTS

Patients ≥35 years that had CHD surgery from 1/1/2007 to 5/1/2017.

OUTCOME MEASURES

Data regarding CAD risk factors and preoperative CAD screening results were obtained. Prevalence and risk factors for CAD were analyzed, along with their relationship to perioperative outcomes.

RESULTS

A total of 73 patients underwent CAD screening with either cardiac catheterization (56%) or computed tomography angiography (34%) prior to CHD surgery. Overall 16 (22%) patients were found to have CAD. Only two patients had severe coronary stenosis and underwent coronary bypass grafting at time of CHD surgery. Patients with CAD were more likely to be older and have history of hypertension, dyslipidemia, and tobacco smoking. CHD diagnosis was not significantly associated with presence of CAD.

CONCLUSION

CAD is common in asymptomatic older patients referred for screening prior to CHD surgery; however, severe CAD requiring concomitant coronary intervention is uncommon. Preoperative CAD screening should be based on age and traditional CAD risk factors, rather than underlying CHD.

摘要

目的

随着先天性心脏病(CHD)成年患者年龄的增长,在CHD手术前可能需要进行冠状动脉疾病(CAD)的术前筛查。关于该人群术前CAD筛查指征的数据有限。目前的做法是遵循瓣膜性心脏病患者的指南;然而,某些先天性心脏病诊断中CAD的风险可能高于一般人群。本研究旨在评估CHD手术患者术前CAD筛查的结果。

设计

回顾性研究。

地点

单一三级中心。

患者

2007年1月1日至2017年5月1日期间接受CHD手术且年龄≥35岁的患者。

观察指标

获取有关CAD危险因素和术前CAD筛查结果的数据。分析CAD的患病率和危险因素,以及它们与围手术期结果的关系。

结果

共有73例患者在CHD手术前接受了CAD筛查,其中56%采用心导管检查,34%采用计算机断层扫描血管造影。总体而言,16例(22%)患者被发现患有CAD。只有2例患者有严重冠状动脉狭窄,并在CHD手术时接受了冠状动脉搭桥术。患有CAD的患者更可能年龄较大,并有高血压、血脂异常和吸烟史。CHD诊断与CAD的存在无显著相关性。

结论

CAD在无症状的老年CHD手术前筛查患者中很常见;然而,需要同时进行冠状动脉干预的严重CAD并不常见。术前CAD筛查应基于年龄和传统CAD危险因素,而非潜在的CHD。

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