Sowunmi O A, Onifade P O
Department of Clinical Services, Neuropsychiatric Hospital Aro, Abeokuta, Ogun, Nigeria.
Niger J Clin Pract. 2019 Sep;22(9):1281-1285. doi: 10.4103/njcp.njcp_325_18.
The Medication Adherence Rating Scale (MARS) is a 10-item self-report measure of medication adherence in psychosis which is a vital predictor of illness course and outcome in patient with schizophrenia. The initial and subsequent studies have shown that MARS has good reliability and validity scores after correction for the small sample size in the index study.
This study aimed to determine the psychometric properties of MARS among outpatients with schizophrenia at the outpatient clinic of the Neuropsychiatric Hospital Aro Abeokuta Ogun State Nigeria.
Intra-class correlation coefficient (ICC) was used to determine the internal consistency, item-total correlations, and reliability of the instrument. Factor analysis was done using principal component analysis with varimax rotation.
The intra-class correlation coefficient (ICC) for these 10 items (at time T) was 0.6 with a P value of <0.001 while for the test--retest analysis was 0.7 with a P value of 0.04. A principal components factor analysis with varimax rotation produced a four-factor solution and factor 4 was found to be the most internally consistent, with Cronbach's alpha of 0.63.
This study supports the internal consistency, test--retest reliability, and constructs validity of the MARS.
药物依从性评定量表(MARS)是一项用于评估精神病患者药物依从性的10项自评量表,而药物依从性是精神分裂症患者病程和预后的重要预测指标。最初及后续研究表明,在对索引研究中的小样本量进行校正后,MARS具有良好的信效度得分。
本研究旨在确定尼日利亚奥贡州阿贝奥库塔阿罗神经精神病医院门诊精神分裂症门诊患者中MARS的心理测量学特性。
采用组内相关系数(ICC)来确定该量表的内部一致性、项目与总分的相关性及信度。使用主成分分析和方差最大旋转进行因子分析。
这10个项目(在T时间点)的组内相关系数(ICC)为0.6,P值<0.001,而重测分析的ICC为0.7,P值为0.04。采用方差最大旋转的主成分因子分析产生了一个四因子解,发现因子4的内部一致性最高,克朗巴哈α系数为0.63。
本研究支持MARS的内部一致性、重测信度和结构效度。