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黄花蒿中 5 种化合物的结构鉴定及抗菌活性研究

Structure elucidation and antimicrobial activities of five compounds from Artemisia integrifolia L.

机构信息

College of Traditional Mongolian Medicine, Inner Mongolia University for Nationalities, Tongliao 028000, Inner Mongolia, China, Fax: +86-0475-8314242.

College of Traditional Mongolian Medicine, Inner Mongolia University for Nationalities, Tongliao 028000, Inner Mongolia, China.

出版信息

Z Naturforsch C J Biosci. 2019 Sep 25;74(9-10):275-278. doi: 10.1515/znc-2018-0208.

DOI:10.1515/znc-2018-0208
PMID:31490779
Abstract

A new compound, integracid (1), together with four known compounds were isolated from the dichloromethane (CH2Cl2) extract from Artemisia integrifolia L. The structures of compounds (1-5) were elucidated by spectroscopic methods, including ultraviolet, infrared (IR), high resolution-electrospray ionization-mass spectrometry (HR-ESI-MS) and extensive one-dimensional (1D) and two-dimensional (2D) nuclear magnetic resonance (NMR) techniques, and by comparison with data reported in the references. Antibacterial activities of the compounds were evaluated against various bacteria.

摘要

从菊科植物黄花蒿 Artemisia integrifolia L. 的二氯甲烷提取物中分离得到一个新的化合物 integracid (1) 以及另外四个已知化合物。通过包括紫外光谱、红外光谱(IR)、高分辨电喷雾电离质谱(HR-ESI-MS)以及广泛的一维(1D)和二维(2D)核磁共振(NMR)技术在内的光谱方法,并与文献报道的数据进行比较,解析了化合物(1-5)的结构。评估了这些化合物对各种细菌的抗菌活性。

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